Optical properties of phosphonium-, quaternary ammonium- and imidazolium- substituted regioregular polythiophenes and application for imaging live cells

被引：11

作者：

Zhang, Chi ^{[1
,2
]}

Du, Ke ^{[1
]}

Zhang, Xiangfei ^{[2
]}

Zheng, Xiaoyu ^{[2
]}

Cao, Guangxiu ^{[2
]}

Zhang, Fuli ^{[2
]}

Feng, Fude ^{[1
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, Dept Polymer Sci & Engn, Nanjing 210023, Jiangsu, Peoples R China

[2] Shangqiu Normal Univ, Sch Chem & Chem Engn, Shangqiu 476000, Peoples R China

来源：

DYES AND PIGMENTS | 2019年 / 170卷

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

Regioregular polythiophenes; Kumada catalyst-transfer polycondensation; Phosphonium; Hyaluronic acid; Cell imaging; HYPERBRANCHED CONJUGATED POLYELECTROLYTE; CHAIN-GROWTH POLYMERIZATION; FUNCTIONALIZED THIOPHENE; CATIONIC POLYTHIOPHENES; FLUORESCENCE; POLYMERS; BINDING; CHARGE; DNA; POLY(3-HEXYLTHIOPHENE);

D O I：

10.1016/j.dyepig.2019.107581

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Cationic side chains on conjugated polyelectrolytes play crucial roles in the state of polymer chains in water as well as the interactions with live cells. However, it is difficult to compare the effect of different cationic side chains due to the structural defect and severe aggregation issue. We synthesized structurally defined cationic polythiophenes with pendent phosphonium-, quaternary ammonium- and imidazolium-substituted side chains, and confirmed molecularly dispersed state of them in aqueous solutions by spectroscopic characterizations. We also investigated the cytotoxicity as well as cell binding and intracellular trafficking by imaging live cells in the absence and presence of hyaluronic acid.

引用

页数：10

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