Diffuse Alveolar Hemorrhage Emerging One Week after Starting High-dose Corticosteroid Therapy for Granulomatosis with Polyangiitis (GPA) with Systemic Lupus Erythematosus (SLE)

被引：5

作者：

Fukui, Shoichi ^{[1
]}

Iwamoto, Naoki ^{[1
]}

Tsuji, Sosuke ^{[1
]}

Umeda, Masataka ^{[1
]}

Nishino, Ayako ^{[1
]}

Nakashima, Yoshikazu ^{[1
]}

Suzuki, Takahisa ^{[1
]}

Horai, Yoshiro ^{[1
]}

Koga, Tomohiro ^{[1
]}

Kawashiri, Shin-ya ^{[1
,2
]}

Ichinose, Kunihiro ^{[1
]}

Hirai, Yasuko ^{[1
]}

Tamai, Mami ^{[1
]}

Nakamura, Hideki ^{[1
]}

Origuchi, Tomoki ^{[1
,3
]}

Kawakami, Atsushi ^{[1
]}

机构：

[1] Nagasaki Univ, Grad Sch Biomed Sci, Dept Immunol & Rheumatol, Nagasaka, Yamanashi, Japan

[2] Nagasaki Univ, Grad Sch Biomed Sci, Dept Publ Hlth, Nagasaka, Yamanashi, Japan

[3] Nagasaki Univ, Grad Sch Biomed Sci, Dept Rehabil Sci, Nagasaka, Yamanashi, Japan

来源：

INTERNAL MEDICINE | 2015年 / 54卷 / 20期

关键词：

ANCA-associated vasculitis; diffuse alveolar hemorrhage; MDS; SLE; ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES; ANCA-ASSOCIATED VASCULITIS; MANIFESTATIONS; CLASSIFICATION; INVOLVEMENT; CRITERIA;

D O I：

10.2169/internalmedicine.54.5299

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 69-year-old man was diagnosed with granulomatosis with polyangiitis (GPA) based on the presence of skin granuloma, refractory otitis media, renal insufficiency and myeloperoxidase-antineutrophil cytoplasmic antibody positivity and slight lung opacity. He was treated with high-dose corticosteroid therapy. Despite the initial improvement of his renal function and a decrease in his C-reactive protein level, he suffered from an alveolar hemorrhage one week after the start of corticosteroid therapy. An anti-dsDNA antibody test was positive and the patient had hypocomplementemia. Elements of both GPA and systemic lupus erythematosus were thought to have affected his clinical course.

引用

页码：2681 / 2686

页数：6

共 17 条

[11] ANCA as a Predictor of Relapse: Useful in Patients with Renal Involvement But Not in Patients with Nonrenal Disease [J].

Kemna, Michael J. ;

Damoiseaux, Jan ;

Austen, Jos ;

Winkens, Bjorn ;

Peters, Jim ;

van Paassen, Pieter ;

Tervaeret, Jan Willem Cohen .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2015, 26 (03) :537-542

[12] Crescentic glomerulonephritis accompanied by myeloperoxidase-antineutrophil cytoplasmic antibodies in a patient having myelodysplastic syndrome with trisomy 7 [J].

Komatsuda, A ;

Miura, I ;

Ohtani, H ;

Hamai, K ;

Wakui, H ;

Imai, H ;

Kobayashi, Y ;

Miura, AB ;

Chubachi, A .

AMERICAN JOURNAL OF KIDNEY DISEASES, 1998, 31 (02) :336-340

[13]

Kostianovsky A, 2012, CLIN EXP RHEUMATOL, V30, pS77

[14] The syndrome of lung hemorrhage and nephritis is usually an ANCA-associated condition [J].

Niles, JL ;

Bottinger, EP ;

Saurina, GR ;

Kelly, KJ ;

Pan, GL ;

Collins, AB ;

McCluskey, RT .

ARCHIVES OF INTERNAL MEDICINE, 1996, 156 (04) :440-445

[15] Derivation and validation of the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus [J].

Petri, Michelle ;

Orbai, Ana-Maria ;

Alarcon, Graciela S. ;

Gordon, Caroline ;

Merrill, Joan T. ;

Fortin, Paul R. ;

Bruce, Ian N. ;

Isenberg, David ;

Wallace, Daniel J. ;

Nived, Ola ;

Sturfelt, Gunnar ;

Ramsey-Goldman, Rosalind ;

Bae, Sang-Cheol ;

Hanly, John G. ;

Sanchez-Guerrero, Jorge ;

Clarke, Ann ;

Aranow, Cynthia ;

Manzi, Susan ;

Urowitz, Murray ;

Gladman, Dafna ;

Kalunian, Kenneth ;

Costner, Melissa ;

Werth, Victoria P. ;

Zoma, Asad ;

Bernatsky, Sasha ;

Ruiz-Irastorza, Guillermo ;

Khamashta, Munther A. ;

Jacobsen, Soren ;

Buyon, Jill P. ;

Maddison, Peter ;

Dooley, Mary Anne ;

van vollenhoven, Ronald F. ;

Ginzler, Ellen ;

Stoll, Thomas ;

Peschken, Christine ;

Jorizzo, Joseph L. ;

Callen, Jeffrey P. ;

Lim, S. Sam ;

Fessler, Barri J. ;

Inanc, Murat ;

Kamen, Diane L. ;

Rahman, Anisur ;

Steinsson, Kristjan ;

Franks, Andrew G., Jr. ;

Sigler, Lisa ;

Hameed, Suhail ;

Fang, Hong ;

Ngoc Pham ;

Brey, Robin ;

Weisman, Michael H. .

ARTHRITIS AND RHEUMATISM, 2012, 64 (08) :2677-2686

[16] Alveolar hemorrhage in systemic lupus erythematosus - Presentation and management [J].

Santos-Ocampo, AS ;

Mandell, BF ;

Fessler, BJ .

CHEST, 2000, 118 (04) :1083-1090

[17] Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiological studies [J].

Watts, Richard ;

Lane, Suzanne ;

Hanslik, Thomas ;

Hauser, Thomas ;

Hellmich, Bernhard ;

Koldingsnes, Wenche ;

Mahr, Alfred ;

Segelmark, Marten ;

Cohen-Tervaert, Jan W. ;

Scott, David .

ANNALS OF THE RHEUMATIC DISEASES, 2007, 66 (02) :222-227

← 1 2 →