Diffuse Alveolar Hemorrhage Emerging One Week after Starting High-dose Corticosteroid Therapy for Granulomatosis with Polyangiitis (GPA) with Systemic Lupus Erythematosus (SLE)

被引：5

作者：

Fukui, Shoichi ^{[1
]}

Iwamoto, Naoki ^{[1
]}

Tsuji, Sosuke ^{[1
]}

Umeda, Masataka ^{[1
]}

Nishino, Ayako ^{[1
]}

Nakashima, Yoshikazu ^{[1
]}

Suzuki, Takahisa ^{[1
]}

Horai, Yoshiro ^{[1
]}

Koga, Tomohiro ^{[1
]}

Kawashiri, Shin-ya ^{[1
,2
]}

Ichinose, Kunihiro ^{[1
]}

Hirai, Yasuko ^{[1
]}

Tamai, Mami ^{[1
]}

Nakamura, Hideki ^{[1
]}

Origuchi, Tomoki ^{[1
,3
]}

Kawakami, Atsushi ^{[1
]}

机构：

[1] Nagasaki Univ, Grad Sch Biomed Sci, Dept Immunol & Rheumatol, Nagasaka, Yamanashi, Japan

[2] Nagasaki Univ, Grad Sch Biomed Sci, Dept Publ Hlth, Nagasaka, Yamanashi, Japan

[3] Nagasaki Univ, Grad Sch Biomed Sci, Dept Rehabil Sci, Nagasaka, Yamanashi, Japan

来源：

INTERNAL MEDICINE | 2015年 / 54卷 / 20期

关键词：

ANCA-associated vasculitis; diffuse alveolar hemorrhage; MDS; SLE; ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES; ANCA-ASSOCIATED VASCULITIS; MANIFESTATIONS; CLASSIFICATION; INVOLVEMENT; CRITERIA;

D O I：

10.2169/internalmedicine.54.5299

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 69-year-old man was diagnosed with granulomatosis with polyangiitis (GPA) based on the presence of skin granuloma, refractory otitis media, renal insufficiency and myeloperoxidase-antineutrophil cytoplasmic antibody positivity and slight lung opacity. He was treated with high-dose corticosteroid therapy. Despite the initial improvement of his renal function and a decrease in his C-reactive protein level, he suffered from an alveolar hemorrhage one week after the start of corticosteroid therapy. An anti-dsDNA antibody test was positive and the patient had hypocomplementemia. Elements of both GPA and systemic lupus erythematosus were thought to have affected his clinical course.

引用

页码：2681 / 2686

页数：6

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