Microwave Imaging for Early Breast Cancer Detection Using a Shape-based Strategy

被引:39
作者
Irishina, Natalia [1 ]
Moscoso, Miguel [1 ]
Dorn, Oliver [1 ]
机构
[1] Univ Carlos III Madrid, Sch Engn, Leganes 78911, Spain
关键词
Early detection of breast tumors; level set technique; microwave imaging; shape reconstruction; tomography; DIELECTRIC-PROPERTIES; TIME-REVERSAL; TOMOGRAPHY; ARRAY; RECONSTRUCTION; LOCALIZATION; TISSUES; DESIGN; SYSTEM; BAND;
D O I
10.1109/TBME.2009.2012398
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In this paper, we propose and analyze a novel shape reconstruction technique for the early detection of breast cancer from microwave data, which is based on a level-set technique. The shape-based approach offers several advantages compared to more traditional pixel-based approaches when targeting the reconstruction of key characteristics of a hidden tumor such as its correct size, shape, and static permittivity value. In addition to these key characteristics of hidden tumors, we aim at estimating the correct interfaces between fatty and fibroglandular tissue in the breast and their internal permittivity profiles. The level set strategy (which is an implicit representation of the shapes) frees us from topological restrictions when reconstructing an a priori arbitrary number of tumors and the often quite complicated interfaces between fatty and fibroglandular regions. The presented strategy is able to detect and, in most cases, characterize tumors whose sizes (diameters) are much smaller than the wavelengths of the electromagnetic waves that are used for illuminating the breast. We present numerical results for a 2-D model with two distinct tissue types (fatty and fibroglandular) in the interior of the breast (in addition to a possible tumor and the surrounding skin). Our results demonstrate the performance and potential of our scheme in various simulated but realistic situations.
引用
收藏
页码:1143 / 1153
页数:11
相关论文
共 45 条
[1]  
ALBERTS B, 1989, MOL BIOL CELL, pCH10
[2]   Microwave imaging via space-time beamforming for early detection of breast cancer [J].
Bond, EJ ;
Li, X ;
Hagness, SC ;
Van Veen, BD .
IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, 2003, 51 (08) :1690-1705
[3]   Optimal waveform design for array imaging [J].
Borcea, Liliana ;
Papanicolaou, George ;
Tsogka, Chrysoula .
INVERSE PROBLEMS, 2007, 23 (05) :1973-2020
[4]   Adaptive interferometric imaging in clutter and optimal illumination [J].
Borcea, Liliana ;
Papanicolaou, George ;
Tsogka, Chrysoula .
INVERSE PROBLEMS, 2006, 22 (04) :1405-1436
[5]   Imaging breast adipose and fibroglandular tissue molecular signatures by using hybrid MRI-guided near-infrared spectral tomography [J].
Brooksby, Ben ;
Pogue, Brian W. ;
Jiang, Shudong ;
Dehghani, Hamid ;
Srinivasan, Subhadra ;
Kogel, Christine ;
Tosteson, Tor D. ;
Weaver, John ;
Poplack, Steven P. ;
Paulsen, Keith D. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (23) :8828-8833
[6]   CYLINDRICAL GEOMETRY - A FURTHER STEP IN ACTIVE MICROWAVE TOMOGRAPHY [J].
BROQUETAS, A ;
ROMEU, J ;
RIUS, JM ;
ELIASFUSTE, AR ;
CARDAMA, A ;
JOFRE, L .
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, 1991, 39 (05) :836-844
[7]   Computational modeling of three-dimensional microwave tomography of breast cancer [J].
Bulyshev, AE ;
Semenov, SY ;
Souvorov, AE ;
Svenson, RH ;
Nazarov, AG ;
Sizov, YE ;
Tatsis, GP .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2001, 48 (09) :1053-1056
[8]  
CHAUDHARY SS, 1984, INDIAN J BIOCHEM BIO, V21, P76
[9]   A computational study of ultra-wideband versus narrowband microwave hyperthermia for breast cancer treatment [J].
Converse, M ;
Bond, EJ ;
Van Veen, BD ;
Hagness, SC .
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, 2006, 54 (05) :2169-2180
[10]   A shape reconstruction method for electromagnetic tomography using adjoint fields and level sets [J].
Dorn, O ;
Miller, EL ;
Rappaport, CM .
INVERSE PROBLEMS, 2000, 16 (05) :1119-1156