Role of Magnesium in Cardiovascular Diseases

被引：160
作者：
Kolte, Dhaval [1 ]
Vijayaraghavan, Krishnaswami [2 ]
Khera, Sahil [1 ]
Sica, Domenic A. [3 ]
Frishman, William H. [1 ]
机构：
[1] New York Med Coll, Dept Med, Div Cardiol, Valhalla, NY 10595 USA
[2] Scottsdale Healthcare, Scottsdale Cardiovasc Ctr, Scottsdale, AZ USA
[3] Virginia Commonwealth Univ Hlth Syst, Div Nephrol, Dept Med & Pharmacol, Richmond, VA USA
来源：
CARDIOLOGY IN REVIEW | 2014年 / 22卷 / 04期
关键词：
magnesium; cardiovascular diseases; hypertension; arrhythmia; ACUTE MYOCARDIAL-INFARCTION; SMOOTH-MUSCLE-CELLS; PAROXYSMAL SUPRAVENTRICULAR TACHYCARDIA; INTRACELLULAR FREE MAGNESIUM; RANDOMIZED CLINICAL-TRIALS; PIG VENTRICULAR MYOCYTES; CONGESTIVE-HEART-FAILURE; CORONARY-ARTERY SURGERY; CAPACITATIVE CA2+ ENTRY; INDUCED QT PROLONGATION;
D O I：
10.1097/CRD.0000000000000003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Magnesium, the fourth most abundant cation in the human body, is involved in several essential physiological, biochemical, and cellular processes regulating cardiovascular function. It plays a critical role in modulating vascular smooth muscle tone, endothelial cell function, and myocardial excitability and is thus central to the pathogenesis of several cardiovascular disorders such as hypertension, atherosclerosis, coronary artery disease, congestive heart failure, and cardiac arrhythmias. This review discusses the vasodilatory, anti-inflammatory, anti-ischemic, and antiarrhythmic properties of magnesium and its current role in the prevention and treatment of cardiovascular disorders.
引用
收藏
页码：182 / 192
页数：11
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