Hemoperfusion for the Treatment of Poisoning: Technology, Determinants of Poison Clearance, and Application in Clinical Practice

被引：87

作者：

Ghannoum, Marc ^{[1
]}

Bouchard, Josee ^{[2
]}

Nolin, Thomas D. ^{[3
]}

Ouellet, Georges ^{[4
]}

Roberts, Darren M. ^{[5
]}

机构：

[1] Univ Montreal, Verdun Hosp, Dept Nephrol, Montreal, PQ, Canada

[2] Univ Montreal, Hop Sacre Coeur Montreal, Dept Nephrol, Montreal, PQ, Canada

[3] Univ Pittsburgh, Sch Pharm, Dept Pharm & Therapeut, Ctr Clin Pharmaceut Sci, Pittsburgh, PA 15261 USA

[4] Univ Montreal, Dept Nephrol, Hop Maison Neuve Rosemont, Montreal, PQ, Canada

[5] Univ Queensland, Sch Med, Burns Trauma & Crit Care Res Ctr, Brisbane, Qld, Australia

来源：

SEMINARS IN DIALYSIS | 2014年 / 27卷 / 04期

关键词：

ACTIVATED-CHARCOAL HEMOPERFUSION; SEVERE DRUG INTOXICATION; AMBERLITE XAD-7 RESIN; CHRONIC-RENAL-FAILURE; ION-EXCHANGE RESINS; IN-VITRO; PARAQUAT REMOVAL; VALPROIC ACID; LONG-TERM; THEOPHYLLINE INTOXICATION;

D O I：

10.1111/sdi.12246

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Hemoperfusion is an extracorporeal treatment based on adsorption, historically reserved for the treatment of acute poisonings. Its use was popularized in the 1970s after several in vitro and animal experiments had demonstrated its efficacy, and was even preferred over hemodialysis in the management of overdosed patients. With the advent of new and more efficient dialytic modalities, hemoperfusion is now less frequently performed in the Western world. However, hemoperfusion still remains popular in developing countries. The present article reviews the technique of hemoperfusion, the factors influencing poison clearance through adsorption and its current applications.

引用

页码：350 / 361

页数：12

共 179 条

[1] REMOVAL OF CHELATED ALUMINUM DURING HEMODIALYSIS USING POLYSULFONE HIGH-FLUX DIALYZERS [J].

AARSETH, HP ;

GANSS, R .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 1990, 5 (11) :942-944

[2]

Ambrus Clara M., 2002, Journal of Medicine (Westbury), V33, P119

[3] LIPID HEMODIALYSIS VERSUS CHARCOAL HEMOPERFUSION IN IMIPRAMINE POISONING [J].

ASBACH, HW ;

HOLZ, F ;

MOHRING, K ;

SCHULER, HW .

CLINICAL TOXICOLOGY, 1977, 11 (02) :211-219

[4] Is Conventional Hemodialysis Enough to Manage Carbamazepine Intoxication? [J].

Azak, Alper ;

Kocak, Gulay ;

Huddam, Bulent ;

Duranay, Murat .

BLOOD PURIFICATION, 2012, 33 (04) :225-226

[5]

Balikova M, 1987, Vnitr Lek, V33, P772

[6] THE PHARMACOKINETICS OF THIABENDAZOLE AND ITS METABOLITES IN AN ANEPHRIC PATIENT UNDERGOING HEMODIALYSIS AND HEMOPERFUSION [J].

BAUER, LA ;

RAISYS, VA ;

WATTS, MT ;

BALLINGER, J .

JOURNAL OF CLINICAL PHARMACOLOGY, 1982, 22 (5-6) :276-280

[7] THE TREATMENT OF SEVERE DRUG INTOXICATION WITH CHARCOAL HEMOPERFUSION IN SERIES WITH HEMODIALYSIS [J].

BENTLEY, C ;

KJELLSTRAND, CM .

JOURNAL OF DIALYSIS, 1979, 3 (04) :337-348

[8] HEMOPERFUSION FOR PHENYLBUTAZONE POISONING [J].

BERLINGER, WG ;

SPECTOR, R ;

FLANIGAN, MJ ;

JOHNSON, GF ;

GROH, MR .

ANNALS OF INTERNAL MEDICINE, 1982, 96 (03) :334-335

[9]

Bouchard N. C., 2005, Clinical Toxicology, V43, P677

[10] HEMOPERFUSION FOR TREATMENT OF N-ACETYLPROCAINAMIDE INTOXICATION [J].

BRADEN, GL ;

FITZGIBBONS, JP ;

GERMAIN, MJ ;

LEDEWITZ, HM .

ANNALS OF INTERNAL MEDICINE, 1986, 105 (01) :64-65

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