The Pathogenesis of Extraintestinal Manifestations: Implications for IBD Research, Diagnosis, and Therapy

被引：164

作者：

Hedin, C. R. H. ^{[1
]}

Vavricka, S. R. ^{[2
]}

Stagg, A. J. ^{[3
]}

Schoepfer, A. ^{[4
,5
]}

Raine, T. ^{[6
]}

Puig, L. ^{[7
]}

Pleyer, U. ^{[8
]}

Navarini, A. ^{[9
]}

van der Meulen-de Jong, A. E. ^{[10
]}

Maul, J. ^{[11
,12
]}

Katsanos, K. ^{[13
]}

Kagramanova, A. ^{[14
]}

Greuter, T. ^{[15
,16
]}

Gonzalez-Lama, V ^{[17
]}

van Gaalen, F. ^{[18
]}

Ellul, P. ^{[19
]}

Burisch, J. ^{[20
,21
]}

Bettenworth, D. ^{[22
]}

Becker, M. D. ^{[23
,24
]}

Barnias, G. ^{[25
]}

Rieder, F. ^{[26
,27
]}

机构：

[1] Karolinska Univ Hosp, Gastroenterol Unit, Patient Area Gastroenterol Dermatovenereol & Rheu, Stockholm, Sweden

[2] Univ Hosp Zurich, Dept Gastroenterol & Hepatol, Zurich, Switzerland

[3] Queen Mary Univ London, Ctr Immunobiol, Barts & London Med Sch, London, England

[4] CHU Vaudois, Div Gastroenterol & Hepatol, Lausanne, Switzerland

[5] Univ Lausanne, Lausanne, Switzerland

[6] Cambridge Univ Teaching Hosp NHS Fdn Trust, Addenbrookes Hosp, Dept Gastroenterol, Cambridge, England

[7] Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Dept Dermatol, Barcelona, Spain

[8] Charite Univ Med Berlin, Univ Eye Clin, Uveitis Ctr, Berlin, Germany

[9] Univ Hosp Zurich, Dept Dermatol, Zurich, Switzerland

[10] Leiden Univ, Dept Gastroenterol, Med Ctr, Leiden, Netherlands

[11] Gastroenterol, Bayer Pl, Berlin, Germany

[12] Charite Univ Med Berlin, Campus Benjamin Franklin, Dept Med, Gastroenterol,Infect Dis,Rheumatol, Berlin, Germany

[13] Univ Ioannina, Sch Med Sci, Dept Internal Med, Div Gastroenterol,Med Sch, Ioannina, Greece

[14] Loginov Moscow Clin Sci Ctr, IBD Dept, Moscow, Russia

[15] Univ Hosp Zurich, Div Gastroenterol & Hepatol, Zurich, Switzerland

[16] Mayo Clin, Gastroenterol Res Unit, Rochester, MN USA

[17] Puerta de Hierro Univ Hosp, Gastroenterol & Hepatol Dept, IBD Unit, Madrid, Spain

[18] Leiden Univ, Med Ctr LUMC, Dept Rheumatol, Leiden, Netherlands

[19] Mater Dei Hosp, Div Gastroenterol, Dept Med, Msida, Malta

[20] Univ Copenhagen, Bispebjerg & Frederiksberg Hosp, Ctr Clin Res & Prevent, Copenhagen, Denmark

[21] Univ Copenhagen, Bispebjerg & Frederiksberg Hosp, Abdominal Ctr K, Med Sect, Copenhagen, Denmark

[22] Univ Hosp Munster, Dept Med B Gastroenterol & Hepatol, Munster, Germany

[23] Triemli Hosp, Dept Ophthalmol, Zurich, Switzerland

[24] Heidelberg Univ, Dept Ophthalmol, Heidelberg, Germany

[25] Univ Athens, GI Unit, Acad Dept Internal Med 3, Sotiria Hosp, Athens, Greece

[26] Cleveland Clin Fdn, Dept Gastroenterol Hepatol & Nutr, 9500 Euclid Ave, Cleveland, OH 44195 USA

[27] Cleveland Clin Fdn, Digest Dis & Surg Inst, 9500 Euclid Ave, Cleveland, OH 44195 USA

来源：

JOURNAL OF CROHNS & COLITIS | 2019年 / 13卷 / 05期

关键词：

ECCO; inflammatory bowel disease; extra-intestinal manifestation; Crohn's disease; ulcerative colitis; spondyloarthritis; uveitis; erythema nodosum; pyoderma gangrenosum; INFLAMMATORY-BOWEL-DISEASE; SOCIETY CLASSIFICATION CRITERIA; PRIMARY SCLEROSING CHOLANGITIS; ANKYLOSING-SPONDYLITIS; GUT MICROBIOTA; TNF-ALPHA; T-CELLS; AXIAL SPONDYLOARTHRITIS; ULCERATIVE-COLITIS; CROHNS-DISEASE;

D O I：

10.1093/ecco-jcc/jjy191

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

This article reports on the sixth scientific workshop of the European Crohn's and Colitis Organisation [ECCO] on the pathogenesis of extraintestinal manifestations [EIMs] in inflammatory bowel disease [IBD]. This paper has been drafted by 15 ECCO members and 6 external experts [in rheumatology, dermatology, ophthalmology, and immunology] from 10 European countries and the USA. Within the workshop, contributors formed subgroups to address specific areas. Following a comprehensive literature search, the supporting text was finalized under the leadership of the heads of the working groups before being integrated by the group consensus leaders.

引用

页码：541 / 554

页数：14

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