Effect of cyclical forces on the periodontal ligament and alveolar bone remodeling during orthodontic tooth movement

被引:49
|
作者
Kalajzic, Zana [1 ]
Peluso, Elizabeth Blake
Utreja, Achint [1 ]
Dyment, Nathaniel [2 ]
Nihara, Jun [1 ]
Xu, Manshan [3 ]
Chen, Jing [3 ]
Uribe, Flavio [1 ]
Wadhwa, Sunil [3 ]
机构
[1] Univ Connecticut, Ctr Hlth, Dept Craniofacial Sci, Farmington, CT 06030 USA
[2] Univ Connecticut, Ctr Hlth, Dept Reconstruct Sci, Farmington, CT 06030 USA
[3] Columbia Univ, Coll Dent Med, Div Orthodont, New York, NY USA
关键词
Orthodontic tooth movement; Cyclical forces; Osteoclasts; Alveolar bone remodeling; VIBRATION; STIMULATION; RESORPTION;
D O I
10.2319/032213-234.1
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Objective: To investigate the effect of externally applied cyclical (vibratory) forces on the rate of tooth movement, the structural integrity of the periodontal ligament, and alveolar bone remodeling. Methods: Twenty-six female Sprague-Dawley rats (7 weeks old) were divided into four groups: CTRL (unloaded), VBO (molars receiving a vibratory stimulus only), TMO (molars receiving an orthodontic spring only), and TMO+VB (molars receiving an orthodontic spring and the additional vibratory stimulus). In TMO and TMO+VB groups, the rat first molars were moved mesially for 2 weeks using Nickel-Titanium coil spring delivering 25 g of force. In VBO and TMO+VB groups, cyclical forces at 0.4 N and 30 Hz were applied occlusally twice a week for 10 minutes. Microfocus X-ray computed tomography analysis and tooth movement measurements were performed on the dissected rat maxillae. Tartrate-resistant acid phosphatase staining and collagen fiber assessment were performed on histological sections. Results: Cyclical forces significantly inhibited the amount of tooth movement. Histological analysis showed marked disorganization of the collagen fibril structure of the periodontal ligament during tooth movement. Tooth movement caused a significant increase in osteoclast parameters on the compression side of alveolar bone and a significant decrease in bone volume fraction in the molar region compared to controls. Conclusions: Tooth movement was significantly inhibited by application of cyclical forces.
引用
收藏
页码:297 / 303
页数:7
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