Cancer of the esophagus and gastric cardia: recent advances

被引:52
作者
Tytgat, GNJ
Bartelink, H
Bernards, R
Giaccone, G
van Lanschot, JJB
Offerhaus, GJA
Peters, GJ
机构
[1] Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands
[2] Netherlands Canc Inst, Amsterdam, Netherlands
[3] Vrije Univ Amsterdam, Med Ctr, Amsterdam, Netherlands
关键词
carcinogenesis; diagnosis; epidemiology; esophageal cancer; gastric neoplasms; therapy;
D O I
10.1111/j.1442-2050.2004.00371.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Esophageal cancer and cancer of the gastric cardia, in particular adenocarcinomas, have shown a rapid and largely unexplained increase in incidence in many developed countries around the world. These diseases have a poor prognosis and current therapies have a modest impact on survival. This review presents recent advances in the epidemiology, etiology, diagnosis, staging, prevention and treatment of resectable and advanced disease. Although significant progress has been made in these areas of research and patient management over the past years, prognosis for most patients diagnosed with esophageal cancer or cancer of the gastric cardia remains poor. New diagnostic procedures, improved surgical procedures, combined treatment modalities and new treatment modalities are being evaluated and may be expected to contribute to improved patient outcomes and better palliation of symptoms in the future.
引用
收藏
页码:10 / 26
页数:17
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