The AvrPm3-Pm3 effector-NLR interactions control both race-specific resistance and host-specificity of cereal mildews on wheat

被引：101

作者：

Bourras, Salim ^{[1
,2
]}

Kunz, Lukas ^{[1
]}

Xue, Minfeng ^{[3
,4
,5
]}

Praz, Coraline Rosalie ^{[1
]}

Mueller, Marion Claudia ^{[1
]}

Kalin, Carol ^{[1
]}

Schlafli, Michael ^{[1
]}

Ackermann, Patrick ^{[1
]}

Fluckiger, Simon ^{[1
]}

Parlange, Francis ^{[1
]}

Menardo, Fabrizio ^{[1
]}

Schaefer, Luisa Katharina ^{[1
]}

Ben-David, Roi ^{[6
]}

Roffler, Stefan ^{[1
]}

Oberhaensli, Simone ^{[1
]}

Widrig, Victoria ^{[1
]}

Lindner, Stefan ^{[1
]}

Isaksson, Jonatan ^{[1
]}

Wicker, Thomas ^{[1
]}

Yu, Dazhao ^{[3
,4
,5
]}

Keller, Beat ^{[1
]}

机构：

[1] Univ Zurich, Dept Plant & Microbial Biol, CH-8008 Zurich, Switzerland

[2] Swedish Univ Agr Sci, Div Plant Pathol, Dept Forest Mycol & Plant Pathol, S-75007 Uppsala, Sweden

[3] Hubei Acad Agr Sci, Inst Plant Protect & Soil Sci, Wuhan 430064, Hubei, Peoples R China

[4] Minist Agr, Key Lab Integrated Pest Management Crops Cent Chi, Wuhan 430064, Hubei, Peoples R China

[5] Wuhan Univ, Coll Life Sci, Wuhan 430072, Hubei, Peoples R China

[6] ARO Volcani Ctr, Inst Plant Sci, IL-50250 Bet Dagan, Israel

来源：

NATURE COMMUNICATIONS | 2019年 / 10卷 / 1期

基金：

瑞士国家科学基金会; 欧洲研究理事会;

关键词：

BLUMERIA-GRAMINIS; AVIRULENCE GENES; FORMAE-SPECIALES; READ ALIGNMENT; POWDERY; DIVERSITY; ALLELES; FUNGUS; IDENTIFICATION; MAINTENANCE;

D O I：

10.1038/s41467-019-10274-1

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The wheat Pm3 resistance gene against the powdery mildew pathogen occurs as an allelic series encoding functionally different immune receptors which induce resistance upon recognition of isolate-specific avirulence (AVR) effectors from the pathogen. Here, we describe the identification of five effector proteins from the mildew pathogens of wheat, rye, and the wild grass Dactylis glomerata, specifically recognized by the PM3B, PM3C and PM3D receptors. Together with the earlier identified AVRPM3(A2/F2), the recognized AVRs of PM3B/C, (AVRPM3(B2/C2)), and PM3D (AVRPM3(D3)) belong to a large group of proteins with low sequence homology but predicted structural similarities. AvrPm3(b2/c2) and AvrPm3(d3) are conserved in all tested isolates of wheat and rye mildew, and non-host infection assays demonstrate that Pm3b, Pm3c, and Pm3d are also restricting the growth of rye mildew on wheat. Furthermore, divergent AVR homologues from non-adapted rye and Dactylis mildews are recognized by PM3B, PM3C, or PM3D, demonstrating their involvement in host specificity.

引用

页数：16

共 69 条

[1] The Barley Powdery Mildew Effector Candidates CSEP0081 and CSEP0254 Promote Fungal Infection Success [J].