Cytotoxicity of six South African medicinal plant extracts used in the treatment of cancer

被引:66
作者
Steenkamp, V. [1 ]
Gouws, M. C. [1 ]
机构
[1] Univ Pretoria, Fac Hlth Sci, Dept Urol, ZA-0001 Pretoria, South Africa
关键词
cancer; cytotoxity; medicinal plants; South Africa;
D O I
10.1016/j.sajb.2006.02.004
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Aqueous extracts prepared from six South African medicinal plants, with cancer-related ethnobotanical uses, were tested for their cytotoxic ability in vitro against three human cancer cell lines: DU-145 prostate cancer cells, MDA-MB-231 and MCF-7 breast cancer cells and a nonmalignant breast cell line, MCF-12A. The plants studied were: Bidens pilosa, Centella asiatica, Cnicus benedictus, Dicoma capensis, Hypoxis hemerocallidea and Sutherlandia ftutescens. Of these plants, only D. capensis exhibited pronounced cytotoxic effects in two of the cell lines tested: MCF-7 and MCF-12A. (c) 2006 SAAB. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:630 / 633
页数:4
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