Current controversies and challenges in allergic rhinitis management

被引：37

作者：

Price, David ^{[1
]}

Smith, Pete ^{[2
]}

Hellings, Peter ^{[3
]}

Papadopoulos, Nikos ^{[4
]}

Fokkens, Wytske ^{[5
]}

Muraro, Antonella ^{[6
]}

Murray, Ruth ^{[7
]}

Chisholm, Alison ^{[8
]}

Demoly, Pascal ^{[9
]}

Scadding, Glenis ^{[10
]}

Mullol, Joaquim ^{[11
]}

Lieberman, Phil ^{[12
]}

Bachert, Claus ^{[13
]}

Moesges, Ralph ^{[14
]}

Ryan, Dermot ^{[15
,16
]}

Bousquet, Jean ^{[17
,18
,19
]}

机构：

[1] Res Real Life, Singapore, Singapore

[2] Griffith Univ, Dept Clin Med, Southport, Qld 4215, Australia

[3] Univ Hosp Leuven, Dept Otorhinolaryngol, Leuven, Belgium

[4] Univ Athens, Dept Allergy, Pediat Clin 2, Athens, Greece

[5] Acad Med Ctr AMC Amsterdam, Dept Otorhinolaryngol, Amsterdam, Netherlands

[6] Padua Univ Hosp, Dept Women & Child Hlth, Food Allergy Referral Ctr, Padua, Italy

[7] Medscript Sci & Med Affairs, Dundalk, Ireland

[8] Resp Effectiveness Grp, Cambridge, England

[9] Univ Hosp Montpellier, Div Allergy, Dept Pulmonol, Hop Arnaud de Villeneuve, Montpellier, France

[10] RNTNE Hosp, London, England

[11] Hosp Clin Barcelona, IDIBAPS, CIBERES, Barcelona, Catalonia, Spain

[12] Univ Tennessee, Coll Med, Memphis, TN USA

[13] Univ Hosp Ghent, Upper Airways Res Lab URL, Ghent, Belgium

[14] Univ Cologne, Fac Med, Inst Med Stat Informat & Epidemiol, D-50931 Cologne, Germany

[15] Univ Edinburgh, Edinburgh, Midlothian, Scotland

[16] Optimum Patient Care, Cambridge, England

[17] Univ Hosp, Montpellier, France

[18] European Innovat Partnership Act & Hlth Ageing Re, Malad Chron Spour Vieillissement Actif Languedoc, MACVIA LR, Paris, France

[19] Univ Versailles St Quentin En Yvelines, UMR S 1168, UVSQ, Versailles, France

来源：

EXPERT REVIEW OF CLINICAL IMMUNOLOGY | 2015年 / 11卷 / 11期

关键词：

allergic rhinitis; clinical relevance; control; guidelines; randomized controlled trials; real life; VISUAL ANALOG SCALE; PRIMARY-CARE ASTHMA; QUALITY-OF-LIFE; BILASTINE; 20; MG; REAL-LIFE; COMBINATION TREATMENT; INTRANASAL THERAPY; DOUBLE-BLIND; EFFICACY; IMPACT;

D O I：

10.1586/1744666X.2015.1081814

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

There are many obstacles in the path of effective allergy management, in general, and allergic rhinitis (AR) control, in particular. Chief among them are: insufficient symptom relief in some patients provided by some currently considered first-line AR treatments in real life; an over-reliance on randomized controlled trials to direct AR guideline recommendations; the need for a broader interpretation of the AR evidence base (to include randomized controlled trials and real-life studies); poorly designed and interpreted studies; and lack of an AR control concept and common language of control. These controversies are fully reviewed here and challenging solutions have been presented.

引用

页码：1205 / 1217

页数：13

共 85 条

[1] Clinical benefits of combination treatment with mometasone furoate nasal spray and loratadine vs monotherapy with mometasone furoate in the treatment of seasonal allergic rhinitis [J].

Anolik, Robert .

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2008, 100 (03) :264-271

[2]

[Anonymous], BMJ

[3]

[Anonymous], 2014, GINA GUIDELINES

[4]

Antonescu E, 2014, EUROPEAN PARLIAMENT

[5] Comparison of the efficacy and safety of bilastine 20 mg vs desloratadine 5 mg in seasonal allergic rhinitis patients [J].

Bachert, C. ;

Kuna, P. ;

Sanquer, F. ;

Ivan, P. ;

Dimitrov, V. ;

Gorina, M. M. ;

van de Heyning, P. ;

Loureiro, A. .

ALLERGY, 2009, 64 (01) :158-165

[6] GRADE guidelines: 3. Rating the quality of evidence [J].

Balshem, Howard ;

Helfand, Mark ;

Schuenemann, Holger J. ;

Oxman, Andrew D. ;

Kunz, Regina ;

Brozek, Jan ;

Vist, Gunn E. ;

Falck-Ytter, Yngve ;

Meerpohl, Joerg ;

Norris, Susan ;

Guyatt, Gordon H. .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 2011, 64 (04) :401-406

[7]

Bartra J, 2007, J INVEST ALLERG CLIN, V17, P3

[8]

Bellanti Joseph A, 2012, Allergy Asthma Proc, V33, P112, DOI 10.2500/aap.2012.33.9001

[9] Allergic and mixed rhinitis: Epidemiology and natural history [J].

Bernstein, Jonathan A. .

ALLERGY AND ASTHMA PROCEEDINGS, 2010, 31 (05) :365-369

[10] Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen) [J].

Bousquet, J. ;

Khaltaev, N. ;

Cruz, A. A. ;

Denburg, J. ;

Fokkens, W. J. ;

Togias, A. ;

Zuberbier, T. ;

Baena-Cagnani, C. E. ;

Canonica, G. W. ;

van Weel, C. ;

Agache, I. ;

Ait-Khaled, N. ;

Bachert, C. ;

Blaiss, M. S. ;

Bonini, S. ;

Boulet, L. -P. ;

Bousquet, P. -J. ;

Camargos, P. ;

Carlsen, K. -H. ;

Chen, Y. ;

Custovic, A. ;

Dahl, R. ;

Demoly, P. ;

Douagui, H. ;

Durham, S. R. ;

van Wijk, R. Gerth ;

Kalayci, O. ;

Kaliner, M. A. ;

Kim, Y. -Y. ;

Kowalski, M. L. ;

Kuna, P. ;

Le, L. T. T. ;

Lemiere, C. ;

Li, J. ;

Lockey, R. F. ;

Mavale-Manuel, S. ;

Meltzer, E. O. ;

Mohammad, Y. ;

Mullol, J. ;

Naclerio, R. ;

Hehir, R. E. O. ;

Ohta, K. ;

Ouedraogo, S. ;

Palkonen, S. ;

Papadopoulos, N. ;

Passalacqua, G. ;

Pawankar, R. ;

Popov, T. A. ;

Rabe, K. F. ;

Rosado-Pinto, J. .

ALLERGY, 2008, 63 :8-+

← 1 2 3 4 5 6 7 8 9 →