Glia in mammalian development and disease

被引:235
作者
Zuchero, J. Bradley [1 ]
Barres, Ben A. [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Neurobiol, Stanford, CA 94305 USA
来源
DEVELOPMENT | 2015年 / 142卷 / 22期
基金
美国国家卫生研究院;
关键词
Astrocyte; Glia; Microglia; Myelination; Nervous system; Oligodendrocyte; WHITE-MATTER; MYELIN; ASTROCYTES; ROLES; CELLS;
D O I
10.1242/dev.129304
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Glia account for more than half of the cells in the mammalian nervous system, and the past few decades have witnessed a flood of studies that detail novel functions for glia in nervous system development, plasticity and disease. Here, and in the accompanying poster, we review the origins of glia and discuss their diverse roles during development, in the adult nervous system and in the context of disease.
引用
收藏
页码:3805 / 3809
页数:5
相关论文
共 51 条
[1]   Microglia: Scapegoat, Saboteur, or Something Else? [J].
Aguzzi, Adriano ;
Barres, Ben A. ;
Bennett, Mariko L. .
SCIENCE, 2013, 339 (6116) :156-161
[2]   Astrocyte Regulation of Synaptic Behavior [J].
Allen, Nicola J. .
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30, 2014, 30 :439-463
[3]   Glial and neuronal control of brain blood flow [J].
Attwell, David ;
Buchan, Alastair M. ;
Charpak, Serge ;
Lauritzen, Martin ;
MacVicar, Brian A. ;
Newman, Eric A. .
NATURE, 2010, 468 (7321) :232-243
[4]   Neural crest origin of olfactory ensheathing glia [J].
Barraud, Perrine ;
Seferiadis, Anastasia A. ;
Tyson, Luke D. ;
Zwart, Maarten F. ;
Szabo-Rogers, Heather L. ;
Ruhrberg, Christiana ;
Liu, Karen J. ;
Baker, Clare V. H. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (49) :21040-21045
[5]   The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease [J].
Barres, Ben A. .
NEURON, 2008, 60 (03) :430-440
[6]   Dynamics and Mechanisms of CNS Myelination [J].
Bercury, Kathryn K. ;
Macklin, Wendy B. .
DEVELOPMENTAL CELL, 2015, 32 (04) :447-458
[7]   Reactive Gliosis and the Multicellular Response to CNS Damage and Disease [J].
Burda, Joshua E. ;
Sofroniew, Michael V. .
NEURON, 2014, 81 (02) :229-248
[8]   Microglia: Multitasking Specialists of the Brain [J].
Casano, Alessandra Maria ;
Peri, Francesca .
DEVELOPMENTAL CELL, 2015, 32 (04) :469-477
[9]   Astrocytes Control Synapse Formation, Function, and Elimination [J].
Chung, Won-Suk ;
Allen, Nicola J. ;
Eroglu, Cagla .
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2015, 7 (09)
[10]   Emerging roles of astrocytes in neural circuit development [J].
Clarke, Laura E. ;
Barres, Ben A. .
NATURE REVIEWS NEUROSCIENCE, 2013, 14 (05) :311-321