Systematic Review of Treatment Effectiveness and Outcome Measures for Enthesitis in Psoriatic Arthritis

被引：46

作者：

Orbai, Ana-Maria ^{[1
]}

Weitz, Joshua ^{[2
]}

Siegel, Evan L. ^{[3
]}

Siebert, Stefan ^{[4
]}

Savage, Laura J. ^{[5
]}

Aydin, Sibel Z. ^{[6
]}

Luime, Jolanda J. ^{[7
]}

Elkayam, Ori ^{[8
,9
]}

Neerinckx, Barbara ^{[10
]}

Urbancek, Slavo ^{[11
]}

de Vlam, Kurt ^{[10
]}

Ritchlin, Christopher T. ^{[12
]}

机构：

[1] Johns Hopkins Arthrit Ctr, Baltimore, MD 21224 USA

[2] Dermatol Associates Rochester, Rochester, MN USA

[3] Arthrit & Rheumatism Associates, Rockville, MD USA

[4] Univ Glasgow, Inst Infect Immun & Inflammat, Glasgow, Lanark, Scotland

[5] Univ Leeds, Leeds Inst Rheumat & Musculoskeletal Med, Leeds, W Yorkshire, England

[6] Koc Univ, Fac Med, Dept Rheumatol, Istanbul, Turkey

[7] Erasmus MC, Dept Rheumatol, Rotterdam, Netherlands

[8] Tel Aviv Univ, Tel Aviv Med Ctr, Dept Rheumatol, IL-69978 Tel Aviv, Israel

[9] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel

[10] Univ Hosp Leuven, Leuven, Belgium

[11] FD Roosevelt Hosp, Dept Dermatol, Banska Bystrica, Slovakia

[12] Univ Rochester, Med Ctr, Div Rheumatol Allergy & Immunol, Rochester, NY 14642 USA

来源：

JOURNAL OF RHEUMATOLOGY | 2014年 / 41卷 / 11期

关键词：

ENTHESITIS; ENTHESOPATHY; PSORIATIC ARTHRITIS; OUTCOME MEASURES; TREATMENT; DOUBLE-BLIND; ANKYLOSING-SPONDYLITIS; MONOCLONAL-ANTIBODY; CONTROLLED TRIAL; PLACEBO; EFFICACY; PHASE-3; SAFETY; USTEKINUMAB; SPONDYLOARTHRITIS;

D O I：

10.3899/jrheum.140878

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Enthesitis is a characteristic feature of psoriatic arthritis (PsA) and is important in disease pathogenesis and classification. Use of clinical outcome measures for enthesitis is heterogeneous, and only 1 measure has been specifically developed and validated in PsA. Ultrasound and magnetic resonance imaging assessments of enthesitis may have advantages over clinical examination but are insufficiently studied. As part of an update of treatment recommendations by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), we performed a systematic literature review and identified randomized controlled trials with enthesitis outcomes in PsA. For each treatment agent we calculated treatment effect sizes (where applicable) and graded the level of evidence.

引用

页码：2290 / 2294

页数：5

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