FK506-induced intractable leukoencephalopathy following allogeneic bone marrow transplantation

被引：21

作者：

Misawa, A

Takeuchi, Y

Hibi, S

Todo, S

Imashuku, S

Sawada, T

机构：

[1] Kyoto Prefectural Univ Med, Dept Pediat, Kamigyo Ku, Kyoto 6028566, Japan

[2] Kyoto City Inst Hlth & Environm Sci, Kyoto, Japan

来源：

BONE MARROW TRANSPLANTATION | 2000年 / 25卷 / 03期

关键词：

FK506; leukoencephalopathy; bone marrow transplantation;

D O I：

10.1038/sj.bmt.1702143

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

FK506-related leukoencephalopathy has been reported to be reversible and readily treated by discontinuation or reduction of FK506, We describe two pediatric cases of FK506-related leukoencephalopathy following allogeneic bone marrow transplantation, which could not be readily controlled. These cases show that FK506-related leukoencephalopathy is not always reversible, and patients may develop epilepsy.

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收藏

页码：331 / 334

页数：4

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