Molecular Epidemiology of Escherichia coli Sequence Type 131 and Its H30 and H30-Rx Subclones among Extended-Spectrum-β-Lactamase-Positive and -Negative E. coli Clinical Isolates from the Chicago Region, 2007 to 2010

被引：102

作者：

Banerjee, Ritu ^{[1
]}

Robicsek, Ari ^{[2
]}

Kuskowski, Michael A. ^{[3
,4
]}

Porter, Stephen ^{[3
,4
]}

Johnston, Brian D. ^{[3
,4
]}

Sokurenko, Evgeni ^{[5
]}

Tchesnokova, Veronika ^{[5
]}

Price, Lance B. ^{[6
,7
]}

Johnson, James R. ^{[3
,4
]}

机构：

[1] Mayo Clin, Rochester, MN USA

[2] NorthShore Univ HealthSyst, Evanston, IL USA

[3] Vet Affairs Med Ctr, Minneapolis, MN USA

[4] Univ Minnesota, Minneapolis, MN USA

[5] Univ Washington, Seattle, WA 98195 USA

[6] Translat Genom Res Inst, Flagstaff, AZ USA

[7] George Washington Univ, Washington, DC USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2013年 / 57卷 / 12期

关键词：

INFECTIONS; ST131;

D O I：

10.1128/AAC.01604-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We assessed Escherichia coli ST131 and its H30 and H30-Rx subclones for virulence genes, antimicrobial resistance, and extended-spectrum beta-lactamase (ESBL) type. Although both subclones were associated with ESBL production, H30-Rx isolates had higher resistance scores and were associated specifically with CTX-M-15. Three virulence genes (iha, sat, and iutA) were more prevalent among H30 than non-H30 ST131 isolates. Thus, the H30 and H30-Rx subclones are more antimicrobial resistant and have virulence profiles that are distinct from those of non-H30 ST131 isolates.

引用

页码：6385 / 6388

页数：4

共 4 条

[1] Prevalence and characteristics of Escherichia coli sequence type 131 and its H30 and H30Rx subclones: a multicenter study from Korea
Kim, Soo-Young
Park, Yeon-Joon
Johnson, James R.
Yu, Jin Kyung
Kim, Yong-Kyun
Kim, Yeong Sic
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2016, 84 (02) : 97 - 101
[2] Intensity and Mechanisms of Fluoroquinolone Resistance within the H30 and H30Rx Subclones of Escherichia coli Sequence Type 131 Compared with Other Fluoroquinolone-Resistant E. coli
Johnson, James R.
Johnston, Brian
Kuskowski, Michael A.
Sokurenko, Evgeni V.
Tchesnokova, Veronika
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2015, 59 (08) : 4471 - 4480
[3] Temporal Trends in Antimicrobial Resistance and Virulence-Associated Traits within the Escherichia coli Sequence Type 131 Clonal Group and Its H30 and H30-Rx Subclones, 1968 to 2012
Olesen, Bente
Frimodt-Moller, Jakob
Leihof, Rikke Fleron
Struve, Carsten
Johnston, Brian
Hansen, Dennis S.
Scheutz, Flemming
Krogfelt, Karen A.
Kuskowski, Michael A.
Clabots, Connie
Johnson, James R.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 58 (11) : 6886 - 6895
[4] Molecular Epidemiological Analysis of Escherichia coli Sequence Type ST131 (O25:H4) and blaCTX-M-15 among Extended-Spectrum-β- Lactamase-Producing E. coli from the United States, 2000 to 2009
Johnson, James R.
Urban, Carl
Weissman, Scott J.
Jorgensen, James H.
Il, James S. Lewis
Hansen, Glen
Edelstein, Paul H.
Robicsek, Ari
Cleary, Timothy
Adachi, Javier
Paterson, David
Quinn, John
Hanson, Nancy D.
Johnston, Brian D.
Clabots, Connie
Kuskowski, Michael A.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 56 (05) : 2364 - 2370

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