A comparison of homologous recombination rates in bacteria and archaea

被引:386
作者
Vos, Michiel [1 ]
Didelot, Xavier [2 ]
机构
[1] Univ Oxford, Dept Zool, Oxford OX1 3PS, England
[2] Univ Warwick, Dept Stat, Coventry CV4 7AL, W Midlands, England
关键词
archaea; bacteria; ClonalFrame; homologous recombination; MLST; SEQUENCE TYPING SCHEME; CLONAL POPULATION-STRUCTURE; GENETIC DIVERSITY; NATURAL-POPULATIONS; ESCHERICHIA-COLI; VIBRIO-PARAHAEMOLYTICUS; EVOLUTION; REVEALS; STRAINS; PATTERNS;
D O I
10.1038/ismej.2008.93
中图分类号
Q14 [生态学(生物生态学)];
学科分类号
071012 ; 0713 ;
摘要
It is a standard practice to test for the signature of homologous recombination in studies examining the genetic diversity of bacterial populations. Although it has emerged that homologous recombination rates can vary widely between species, comparing the results from different studies is made difficult by the diversity of estimation methods used. Here, Multi Locus Sequence Typing (MLST) datasets from a wide variety of bacteria and archaea are analyzed using the ClonalFrame method. This enables a direct comparison between species and allows for a first exploration of the question whether phylogeny or ecology is the primary determinant of homologous recombination rate.
引用
收藏
页码:199 / 208
页数:10
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