Behavioural and neuropsychiatric disturbance in three clinical subtypes of frontotemporal dementia: A Clinical Research Center for Dementia of South Korea-FTD Study

被引:7
作者
Park, Moon Ho [1 ,2 ]
Kim, Eun-Joo [3 ,4 ]
Park, Kyung Won [5 ]
Kwon, Jae Cheol [6 ]
Ku, Bon D. [7 ]
Han, Seol-Heui [8 ,9 ]
Kim, SangYun [10 ,11 ]
Yang, Dong Won [12 ]
Na, Duk L. [13 ]
Choi, Seong Hye [14 ]
机构
[1] Korea Univ, Dept Neurol, Coll Med, Ansan, South Korea
[2] Korea Univ, Ansan Hosp, Ansan, South Korea
[3] Pusan Natl Univ, Sch Med, Pusan Natl Univ Hosp, Dept Neurol, Busan, South Korea
[4] Med Res Inst, Busan, South Korea
[5] Dong A Univ, Coll Med, Dong A Med Ctr, Dept Neurol, Busan, South Korea
[6] Changwon Fatima Hosp, Dept Neurol, Chang Won, South Korea
[7] Catholic Kwandong Univ, Dept Neurol, Coll Med, Kangnung, South Korea
[8] Konkuk Univ, Dept Neurol, Med Ctr, Seoul, South Korea
[9] Konkuk Univ, Sch Med, Seoul, South Korea
[10] Seoul Natl Univ, Coll Med, Dept Neurol, Seoul, South Korea
[11] Seoul Natl Univ, Bundang Hosp, Clin Neurosci Ctr, Seoul, South Korea
[12] Catholic Univ Korea, Dept Neurol, Coll Med, Dept Neurol, Seoul, South Korea
[13] Sungkyunkwan Univ, Dept Neurol, Samsung Med Ctr, Sch Med, Seoul, South Korea
[14] Inha Univ, Dept Neurol, Sch Med, Incheon, South Korea
基金
新加坡国家研究基金会;
关键词
behavioural symptoms; brief psychiatric rating scale; frontotemporal dementia; PRIMARY-PROGRESSIVE-APHASIA; ALZHEIMERS-DISEASE; SEMANTIC DEMENTIA; DIAGNOSTIC-CRITERIA; LOBAR DEGENERATION; TEMPORAL VARIANTS; INVENTORY; FEATURES; COGNITION;
D O I
10.1111/ajag.12374
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
ObjectivesTo characterise the behavioural and neuropsychiatric disturbances of patients with three clinical subtypes of frontotemporal dementia (FTD): behavioural variant FTD (bvFTD), semantic dementia (SD) and progressive non-fluent aphasia (PNFA). MethodsConsecutive series of 66 patients with bvFTD, 58 patients with SD and 21 patients with PNFA were compared using the Frontal Behavioural Inventory (FBI) and the Neuropsychiatric Inventory (NPI). ResultsPatients with bvFTD had more behavioural and neuropsychiatric disturbances than patients with PNFA based on the total scores of FBI and NPI. When comparing subtotal and item scores of FBI and NPI, there were some significant differences among three clinical subtypes of FTD. ConclusionThere are some distinct patterns of behavioural and neuropsychiatric disturbance among three clinical subtypes of FTD.
引用
收藏
页码:46 / 51
页数:6
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