Optical rotation: Recent advances in determining the absolute configuration

被引：247

作者：

Polavarapu, PL ^{[1
]}

机构：

[1] Vanderbilt Univ, Dept Chem, Nashville, TN 37235 USA

来源：

CHIRALITY | 2002年 / 14卷 / 10期

关键词：

optical rotation; specific rotation; absolute configuration; ab initio; quantum mechancal predictions;

D O I：

10.1002/chir.10145

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The field of optical rotations is currently undergoing a renaissance, which is a direct result of the advances in quantum mechanics and the availability of faster desktop computers. In the last few years, the field of optical rotations has taken an important role for determining the three-dimensional molecular structure (absolute configuration and conformations) with confidence. The purpose of this review is to present the latest advances in this area so that practicing chemists can utilize them in their respective areas of research and development. (C) 2002 Wiley-Liss, Inc.

引用

页码：768 / 781

页数：14

共 87 条

[1] ELECTRIC AND MAGNETIC-PROPERTIES OF CO,HF,HCL AND CH3F [J].