Developing safe therapies from human pluripotent stem cells

被引：88
作者：
Carpenter, Melissa K. [1 ]
Frey-Vasconcells, Joyce [2 ]
Rao, Mahendra S. [3 ]
机构：
[1] Carpenter Grp, San Diego, CA USA
[2] Pharmanet Consulting, Princeton, NJ USA
[3] Invitrogen Corp, Frederick, MD USA
来源：
NATURE BIOTECHNOLOGY | 2009年 / 27卷 / 07期
关键词：
PARKINSONS-DISEASE; GENE-EXPRESSION; HUMAN ES; LINES; TRANSPLANTATION; GENERATION; SURVIVAL; DIFFERENTIATION; TUMORS; INACTIVATION;
D O I：
10.1038/nbt0709-606
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Translation of human pluripotent stem cells into cell therapies will require the development of standardized tests for product consistency, stability, tumorigenicity, toxicity and immunogenicity.
引用
收藏
页码：606 / 613
页数：8
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