The structure of the polysaccharide isolated from Acinetobacter baumannii strain LAC-4

被引:31
作者
Vinogradov, Evgeny [1 ]
MacLean, Leann [1 ]
Xu, H. Howard [2 ]
Chen, Wangxue [1 ]
机构
[1] Natl Res Council Canada, Ottawa, ON K1A 0R6, Canada
[2] Calif State Univ Los Angeles, Dept Biol Sci, Los Angeles, CA 90032 USA
关键词
Acinetobacter; Acinetobacter baumannii; LPS; O-Polysaccharide; Structure; NMR; O-ANTIGENIC POLYSACCHARIDE; SEROLOGICAL CHARACTERIZATION; LIPOPOLYSACCHARIDE; ACID; IDENTIFICATION; HAEMOLYTICUS; PNEUMONIA; O-12;
D O I
10.1016/j.carres.2014.03.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The structure of the surface polysaccharide from a hypervirulent for mice Acinetobacter baumannii strain LAC-4 was studied. The polysaccharide was built of trisaccharide repeating units containing alpha-L-fucosamine, alpha-D-glucosamine, and alpha-8-epi-legionaminic acid. The structure interpretation was based mostly on NMR data. Polysaccharide was obtained using a procedure of LPS O-chain preparation, although whether it is an LPS O-chain or capsular polysaccharide remained unclear. Crown Copyright (C) 2014 Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:42 / 45
页数:4
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