Cerebrospinal Fluid Immunoglobulins as Potential Biomarkers of Chikungunya Encephalitis

被引：8
作者：
Puccioni-Sohler, Marzia [1 ,2 ]
Farias, Luiz Claudio [1 ]
Cabral-Castro, Mauro Jorge [1 ]
Zalis, Mariano G. [1 ]
Kalil, Rosangela S. [2 ]
Salgado, Maria Cecilia F. [2 ]
机构：
[1] Univ Fed Rio de Janeiro, Rio De Janeiro, Brazil
[2] Univ Fed Estado Rio de Janeiro, Rio De Janeiro, Brazil
来源：
EMERGING INFECTIOUS DISEASES | 2018年 / 24卷 / 05期
关键词：
HUMORAL IMMUNE-RESPONSE; VIRUS;
D O I：
10.3201/eid2405.171763
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Chikungunya virus causes fever and severe polyarthritis or arthralgia and is associated with neurologic manifestations that are sometimes challenging to diagnose. We demonstrate intrathecal synthesis of chikungunya antibodies in a patient with a history of acute infection complicated by encephalitis. The specificity of the intracerebral immune response supports early chikungunya-associated encephalitis diagnosis.
引用
收藏
页码：939 / 941
页数：3
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