A New Flavone from the Leaves of Astronia formosana

被引：0

作者：

Chen, Yu-Chang ^{[1
,2
]}

Weng, Jing-Ru ^{[3
,4
]}

机构：

[1] Kaohsiung Med Univ, Coll Pharm, Sch Pharm, Kaohsiung 80708, Taiwan

[2] Kaohsiung Med Univ Hosp, Dept Med Res, Kaohsiung 80708, Taiwan

[3] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung 80424, Taiwan

[4] Natl Sun Yat Sen Univ, Doctoral Degree Program Marine Biotechnol, Kaohsiung 80424, Taiwan

来源：

NATURAL PRODUCT COMMUNICATIONS | 2018年 / 13卷 / 06期

关键词：

Astronia formosana; Melastomataceae; Leaves; Cytotoxicity; 6,8-Di-C-methyl flavonoid; 5,4 '-Dihydroxy-7,3 '-dimethoxy-6,8-dimethylflavone; CONSTITUENTS;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new flavone, 5,4'-dihydroxy-7,3'-dimethoxy-6,8-dimethylflavone (1), together with four known compounds, ursolic acid (2), beta-sitosterol-beta-D-glucoside (3), beta-sitosterol (4) and lupeol (5) were isolated from the methanolic extract of the leaves of Astronia formosana. The structures were elucidated on the basis of physical and spectroscopic data analyses. Compound 1 showed the slight cytotoxicity against MCF-7, SCM-1, and SCC2095 cell lines with IC50 values of 29.3 +/- 9.2, 20.5 +/- 10.2, and 25.7 +/- 2.9 mu M, respectively.

引用

页码：691 / 692

页数：2

共 13 条

[1] Bai LY, 2014, NAT PROD COMMUN, V9, P1557
[2] STEROIDS AND TRITERPENOIDS FROM ROSA-LAEVIGATA
FANG, JM
WANG, KC
CHENG, YS
[J]. PHYTOCHEMISTRY, 1991, 30 (10) : 3383 - 3387
[3] Gan WS., 1965, MANUAL MED PLANTS TA, V3, P622
[4] GUPTA DR, 1984, INDIAN J CHEM B, V23, P682
[5] VARIETAL SIMILARITIES AND DIFFERENCES IN THE POLYCYCLIC ISOPENTENOID COMPOSITION OF SORGHUM
HEUPEL, RC
[J]. PHYTOCHEMISTRY, 1985, 24 (12) : 2929 - 2937
[6] Biological screening of rain forest plot trees from Palawan Island (Philippines)
Horgen, FD
Edrada, RA
de los Reyes, G
Agcaoili, F
Madulid, DA
Wongpanich, V
Angerhofer, CK
Pezzuto, JM
Soejarto, DD
Farnsworth, NR
[J]. PHYTOMEDICINE, 2001, 8 (01) : 71 - 81
[7] Huang SF, 1993, FLORA TAIWAN, V3, P905
[8] Hwang BY, 2003, PLANTA MED, V69, P623, DOI 10.1055/s-2003-41115
[9] CONSTITUENTS OF THE LABIATAE PLANTS .5. STEROL GLUCOSIDES FROM PRUNELLA-VULGARIS
KOJIMA, H
SATO, N
HATANO, A
OGURA, H
[J]. PHYTOCHEMISTRY, 1990, 29 (07) : 2351 - 2355
[10] Komuraiah B, 2014, LEAF PHCOG J, V6, P83

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