Spectrum of anti-measles immunoglobulin G subclasses in convalescents after measles

被引：6
作者：
Toptygina, AP [1 ]
Pukhal'skii, AL
Mamaeva, TA
Aleshkin, VA
机构：
[1] Russian Acad Med Sci, Med Genet Res Ctr, Moscow, Russia
[2] GN Gabrichevskii Epidemiol & Microbiol Res Inst, Moscow, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2004年 / 137卷 / 03期
关键词：
IgG subclasses; measles;
D O I：
10.1023/B:BEBM.0000031564.27747.b4
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
A simple semiquantitative method for measuring anti-measles IgG subclasses is developed on the basis of commercial diagnostic test system for measurements of anti-measles IgG and a kit of peroxidase-labeled monoclonal antibodies to human IgG subclasses. During the acute phase of the disease specific antibodies are presented mainly by IgG2 antibodies, while in subjects with a history of measles more than 10 years before 2 subgroups were detected, which responded by production of IgG2 or IgG1 subclasses.
引用
收藏
页码：259 / 261
页数：3
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