Human papillomavirus (HPV) deregulation of Toll-like receptor 9

被引：21
|
作者：
Hasan, Uzma [1 ]
机构：
[1] Univ Lyon, Hosp Civils Lyon, Ecole Normale Super, INSERM U1111,CNRS UMR5308,CIRI, Lyon, France
来源：
ONCOIMMUNOLOGY | 2014年 / 3卷 / 01期
关键词：
E7; HPV16; immunosuppression; TLR9; CERVICAL-CANCER; RECOGNITION; EXPRESSION; TYPE-16; TLR9;
D O I：
10.4161/onci.27257
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Persistent infection by high- risk human papillomavirus (HPV) is associated with cervical carcinoma. Blocking innate immune responses in the cervix is critical for the establishment of persistent infections. Here, we discuss how HPV-16-encoded factors suppress the activity of Toll-like receptor 9, which plays a major role in innate antiviral immune responses.
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Cleavage of Toll-Like Receptor 9 Ectodomain Is Required for In Vivo Responses to Single Strand DNA
    Fukui, Ryutaro
    Yamamoto, Chikako
    Matsumoto, Fumi
    Onji, Masahiro
    Shibata, Takuma
    Murakami, Yusuke
    Kanno, Atsuo
    Hayashi, Takuto
    Tanimura, Natsuko
    Yoshida, Nobuaki
    Miyake, Kensuke
    FRONTIERS IN IMMUNOLOGY, 2018, 9
  • [42] Regulation of migration and invasion by Toll-like receptor-9 signaling network in prostate cancer
    Luo, Yun
    Jiang, Qi-Wei
    Wu, Jie-Ying
    Qiu, Jian-Ge
    Zhang, Wen-Ji
    Mei, Xiao-Long
    Shi, Zhi
    Di, Jin-Ming
    ONCOTARGET, 2015, 6 (26) : 22564 - 22574
  • [43] Toll-Like Receptor Agonists: Can They Exact a Toll on Human Immunodeficiency Virus Persistence?
    Cyktor, Joshua C.
    Mellors, John W.
    CLINICAL INFECTIOUS DISEASES, 2017, 64 (12) : 1696 - 1698
  • [44] Toll-Like Receptor Agonists as Adjuvants for HIV Vaccines
    Stevceva, L.
    CURRENT MEDICINAL CHEMISTRY, 2011, 18 (33) : 5079 - 5082
  • [45] Deviation from major codons in the Toll-like receptor genes is associated with low Toll-like receptor expression
    Zhong, F
    Cao, WP
    Chan, E
    Tay, PN
    Cahya, FF
    Zhang, HF
    Lu, JH
    IMMUNOLOGY, 2005, 114 (01) : 83 - 93
  • [46] Toll-Like Receptor 2 or Toll-Like Receptor 4 Deficiency Does Not Modify Lupus in MRLlpr Mice
    Freeley, Simon J.
    Giorgini, Angela
    Tulone, Calogero
    Popat, Reena J.
    Horsfield, Catherine
    Robson, Michael G.
    PLOS ONE, 2013, 8 (09):
  • [47] Toll-like Receptor 10 in Helicobacter pylori Infection
    Nagashima, Hiroyuki
    Iwatani, Shun
    Cruz, Modesto
    Jimenez Abreu, Jose A.
    Uchida, Tomohisa
    Mahachai, Varocha
    Vilaichone, Ratha-korn
    Graham, David Y.
    Yamaoka, Yoshio
    JOURNAL OF INFECTIOUS DISEASES, 2015, 212 (10) : 1666 - 1676
  • [48] Rethinking Toll-like receptor signalling
    Bryant, Clare E.
    CURRENT OPINION IN IMMUNOLOGY, 2024, 91
  • [49] Role of atopic status in Toll-like receptor (TLR)7-and TLR9-mediated activation of human eosinophils
    Mansson, Anne
    Cardell, Lars-Olaf
    JOURNAL OF LEUKOCYTE BIOLOGY, 2009, 85 (04) : 719 - 727
  • [50] Effects of Toll-like receptor 7 and Toll-like receptor 9 signaling stimulators and inhibitors on chronic lymphocytic leukemia cells ex vivo and their interactions with cladribine
    Wolska, Anna
    Cebula-Obrzut, Barbara
    Smolewski, Piotr
    Robak, Tadeusz
    LEUKEMIA & LYMPHOMA, 2013, 54 (06) : 1268 - 1278
12345