Human papillomavirus (HPV) deregulation of Toll-like receptor 9

被引：21
|
作者：
Hasan, Uzma [1 ]
机构：
[1] Univ Lyon, Hosp Civils Lyon, Ecole Normale Super, INSERM U1111,CNRS UMR5308,CIRI, Lyon, France
来源：
ONCOIMMUNOLOGY | 2014年 / 3卷 / 01期
关键词：
E7; HPV16; immunosuppression; TLR9; CERVICAL-CANCER; RECOGNITION; EXPRESSION; TYPE-16; TLR9;
D O I：
10.4161/onci.27257
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Persistent infection by high- risk human papillomavirus (HPV) is associated with cervical carcinoma. Blocking innate immune responses in the cervix is critical for the establishment of persistent infections. Here, we discuss how HPV-16-encoded factors suppress the activity of Toll-like receptor 9, which plays a major role in innate antiviral immune responses.
引用
收藏
页数：3
相关论文
共 50 条
  • [31] SYNAPTIC ABNORMALITIES OF MICE LACKING TOLL-LIKE RECEPTOR (TLR)-9
    Patel, V.
    Patel, A. M.
    McArdle, J. J.
    NEUROSCIENCE, 2016, 324 : 1 - 10
  • [32] Sequence and functional variability of Toll-like receptor 9 gene in equines
    Manuja, Anju
    Manuja, Balvinder K.
    Singha, Harisankar
    MOLECULAR IMMUNOLOGY, 2019, 105 : 276 - 282
  • [33] The involvement of Toll-like receptor 9 in the pathogenesis of erosive autoimmune arthritis
    Fischer, Anita
    Abdollahi-Roodsaz, Shahla
    Boehm, Christina
    Niederreiter, Birgit
    Meyer, Brigitte
    Yau, Anthony C. Y.
    Lonnblom, Erik
    Joosten, Leo A. B.
    Koenders, Marije
    Lehmann, Christian H. K.
    Dudziak, Diana
    Kroenke, Gerhard
    Holmdahl, Rikard
    Steiner, Guenter
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018, 22 (09) : 4399 - 4409
  • [34] Involvement of toll-like receptor 9 polymorphism in cervical cancer development
    Roszak, Andrzej
    Lianeri, Margarita
    Sowinska, Anna
    Jagodzinski, Pawel P.
    MOLECULAR BIOLOGY REPORTS, 2012, 39 (08) : 8425 - 8430
  • [35] Association of Toll-like receptor 3 and Toll-like receptor 9 single-nucleotide polymorphisms with hepatitis C virus persistence among Egyptians
    Hamdy, Shaimaa
    Osman, Ahmed M.
    Zakaria, Zainab A.
    Galal, Iman
    Sobhy, Maha
    Hashem, Mohamed
    Allam, Walaa R.
    Abdel-Samiee, Mohamed
    Rewisha, Eman
    Waked, Imam
    Abdelwahab, Sayed F.
    ARCHIVES OF VIROLOGY, 2018, 163 (09) : 2433 - 2442
  • [36] Salivary and Plasma Levels of Toll-Like Receptor 2 and Toll-Like Receptor 4 in Chronic Periodontitis
    Buduneli, Nurcan
    Ozcaka, Ozgun
    Nalbantsoy, Ayse
    JOURNAL OF PERIODONTOLOGY, 2011, 82 (06) : 878 - 884
  • [37] Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma
    Xun, Yang
    Yang, Hua
    Kaminska, Bozena
    You, Hua
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 14 (01)
  • [38] Toll-like receptor bioactivity in endothelial progenitor cells
    Heidarzadeh, Morteza
    Roodbari, Fatemeh
    Hassanpour, Mehdi
    Ahmadi, Mahdi
    Saberianpour, Shirin
    Rahbarghazi, Reza
    CELL AND TISSUE RESEARCH, 2020, 379 (02) : 223 - 230
  • [39] Menstrual Cycle Influences Toll-Like Receptor Responses
    Dennison, Una
    McKernan, Declan P.
    Scully, Paul
    Clarke, Gerard
    Cryan, John
    Dinan, Timothy
    NEUROIMMUNOMODULATION, 2012, 19 (03) : 171 - 179
  • [40] An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing
    Onji, Masahiro
    Kanno, Atsuo
    Saitoh, Shin-Ichiroh
    Fukui, Ryutaro
    Motoi, Yuji
    Shibata, Takuma
    Matsumoto, Fumi
    Lamichhane, Aayam
    Sato, Shintaro
    Kiyono, Hiroshi
    Yamamoto, Kazuhide
    Miyake, Kensuke
    NATURE COMMUNICATIONS, 2013, 4
12345