PDZ domain proteins: Scaffolds for signaling complexes

被引：114
|
作者：
Ranganathan, R [1 ]
Ross, EM [1 ]
机构：
[1] UNIV TEXAS,SW MED CTR,DEPT PHARMACOL,DALLAS,TX 75235
来源：
CURRENT BIOLOGY | 1997年 / 7卷 / 12期
关键词：
D O I：
10.1016/S0960-9822(06)00401-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision, Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.
引用
收藏
页码：R770 / R773
页数：4
相关论文
共 50 条
  • [31] Identification of functional PDZ domain binding sites in several human proteins
    Fabre, S
    Reynaud, C
    Jalinot, P
    MOLECULAR BIOLOGY REPORTS, 2000, 27 (04) : 217 - 224
  • [32] Possible role for PDZ domain-containing proteins in lens development
    Nguyen, MM
    Griep, AE
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2002, 43 : U93 - U93
  • [33] Possible role for PDZ domain containing proteins in lens development.
    Nguyen, MM
    Griep, AE
    DEVELOPMENTAL BIOLOGY, 2002, 247 (02) : 477 - 477
  • [34] Cloning and characterization of novel PDZ-domain including proteins in the heart
    Murata, M
    Koren, G
    CIRCULATION, 1998, 98 (17) : 11 - 11
  • [35] The binding affinities of proteins interacting with the PDZ domain of PICK1
    Bolia, Ashini
    Gerek, Z. Nevin
    Keskin, Ozlem
    Ozkan, Sefika Banu
    Dev, Kumlesh K.
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2012, 80 (05) : 1393 - 1408
  • [36] In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
    Wu, Yanning
    Wang, Shuo
    Li, Chunying
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2012, (66):
  • [37] Role of PDZ domain-containing proteins and ERM proteins in regulation of renal function and dysfunction
    Levi, M
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2003, 14 (07): : 1949 - 1951
  • [38] Oracle, a PDZ and LIM domain-containing protein, participates in PKCε protective signaling complexes at distinct subcellular locations in the heart
    Zheng, YT
    Vondriska, TM
    Zhang, J
    Edmondson, R
    Ping, PP
    CIRCULATION, 2002, 106 (19) : 312 - 312
  • [39] The multi PDZ domain protein MUPP1 as a putative scaffolding protein for organizing signaling complexes in the acrosome of mammalian spermatozoa
    Heydecke, D
    Meyer, D
    Ackermann, F
    Wilhelm, B
    Gudermann, T
    Boekhoff, I
    JOURNAL OF ANDROLOGY, 2006, 27 (03): : 390 - 404
  • [40] Assembling proteins with modular DNA scaffolds: a strategy for engineering antibodies and probing cellular signaling complexes.
    Liang, S. I.
    McFarland, J. M.
    Rabuka, D.
    Gartner, Z. J.
    MOLECULAR BIOLOGY OF THE CELL, 2014, 25
12345