PDZ domain proteins: Scaffolds for signaling complexes

被引:114
|
作者
Ranganathan, R [1 ]
Ross, EM [1 ]
机构
[1] UNIV TEXAS,SW MED CTR,DEPT PHARMACOL,DALLAS,TX 75235
关键词
D O I
10.1016/S0960-9822(06)00401-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision, Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.
引用
收藏
页码:R770 / R773
页数:4
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