Risk Factors for Incident Dementia Among Older Cubans

被引:9
作者
Peeters, Geeske [1 ,2 ]
Almirall Sanchez, Arianna [1 ,2 ]
Llibre Guerra, Jorge [1 ,2 ,3 ]
Lawlor, Brian [1 ,2 ,4 ]
Kenny, Rose Anne [1 ,2 ,5 ]
Yaffe, Kristine [1 ,2 ,6 ]
Llibre Rodriguez, Juan [7 ]
机构
[1] Trinity Coll Dublin, Global Brain Hlth Inst, Dublin, Ireland
[2] Univ Calif San Francisco, Global Brain Hlth Inst, San Francisco, CA 94143 USA
[3] Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA
[4] St James Hosp, Mercers Inst Successful Ageing, Dept Psychiat, Dublin, Ireland
[5] Trinity Coll Dublin, Irish Longitudinal Study Ageing, Dublin, Ireland
[6] Univ Calif San Francisco, Dept Psychiat Neurol & Epidemiol, San Francisco, CA 94143 USA
[7] Univ Ciencias Med Habana, Fac Med Finley Albarran, Havana, Cuba
基金
英国惠康基金;
关键词
dementia; risk profile; lifestyle; older adults; epidemiology; APOLIPOPROTEIN-E GENOTYPE; COGNITIVE IMPAIRMENT; ALZHEIMERS-DISEASE; DEVELOPING-COUNTRIES; BLOOD-PRESSURE; LOW-INCOME; ASSOCIATION; PREVALENCE; AGE;
D O I
10.3389/fpubh.2020.00481
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Introduction:Little is known about risk factors of dementia in Latin American countries. We aimed to identify socio-demographic, health and lifestyle risk factors of incident dementia in Cuban older adults. Methods:Data were from 1,846 participants in the Cuban cohort of the 10/66 Dementia Research Group. Participants completed questionnaires, health examinations, and cognitive tests at baseline (2003-2006) and 4.5 years later (2007-2010). Associations between risk factors (baseline) and incident dementia (follow-up) were examined using logistic regression. Results:Just over 9% of participants developed dementia. Overall, older age and low physical activity were associated with incident dementia. In those 65-74 years of age, depression, stroke and low physical activity were associated with incident dementia. In those >= 75 years of age, low physical activity, never eating fish, and smoking were associated with incident dementia. Conclusions:Modifiable lifestyle factors play an important role in developing dementia in Cuban older adults. This knowledge opens up opportunities for preventive strategies.
引用
收藏
页数:10
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