Amide-Ligand-Controlled Highly para-Selective Arylation of Monosubstituted Simple Arenes with Arylboronic Acids

被引：64

作者：

Luan, Yu-Xin ^{[1
,2
]}

Zhang, Tao ^{[1
,2
]}

Yao, Wei-Wei ^{[1
,2
]}

Lu, Ke ^{[1
,2
]}

Kong, Lu-Yao ^{[1
,2
]}

Lin, Yu-Tong ^{[1
,2
]}

Ye, Mengchun ^{[1
,2
,3
]}

机构：

[1] Nankai Univ, State Key Lab, Tianjin 300071, Peoples R China

[2] Nankai Univ, Inst Elementoorgan Chem, Tianjin 300071, Peoples R China

[3] Nankai Univ, Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 139卷 / 05期

基金：

中国国家自然科学基金;

关键词：

CATALYZED DIRECT ARYLATION; C-H ACTIVATION; ELECTRON-DEFICIENT POLYFLUOROARENES; CROSS-COUPLING REACTIONS; ARYL BOND FORMATION; UNACTIVATED ARENES; SODIUM PERSULFATE; ROOM-TEMPERATURE; PALLADIUM; FUNCTIONALIZATION;

D O I：

10.1021/jacs.6b12907

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pd-catalyzed highly para-selective arylations of monosubstituted simple arenes with arylboronic acids to widely existed biaryls have been developed. Inspired by requisite amide-directing groups in reported selective oxidative couplings, amide ligands, especially DMF, are designed and found to be critical for the selectivity control in current arylations.

引用

页码：1786 / 1789

页数：4

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