Visible light mediated intermolecular [3+2] annulation of cyclopropylanilines with alkynes

被引：48
作者：
Nguyen, Theresa H. [1 ]
Maity, Soumitra [1 ]
Zheng, Nan [1 ]
机构：
[1] Univ Arkansas, Dept Chem & Biochem, Fayetteville, AR 72701 USA
来源：
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 10卷
基金：
美国国家卫生研究院; 美国国家科学基金会;
关键词：
3+2; alkyne; annulation; cyclopropylaniline; photoredox catalysis; visible light; PHOTOREDOX CATALYSIS; TERTIARY AMINOCYCLOPROPANES; N-CYCLOPROPYLANILINES; MECHANISTIC PROBES; AEROBIC OXIDATION; RING; DERIVATIVES; RADICALS; ROUTES;
D O I：
10.3762/bjoc.10.96
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Intermolecular [3 + 2] annulation of cyclopropylanilines with alkynes is realized using visible light photoredox catalysis, yielding a variety of cyclic allylic amines in fair to good yields. This method exhibits significant group tolerance particularly with heterocycles. It can also be used to prepare complex heterocycles such as fused indolines.
引用
收藏
页码：975 / 980
页数：6
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