Calorimetric studies of the action of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride on the growth of microorganisms

被引：166
作者：
Qin, CQ
Xiao, Q
Li, HR
Fang, M
Liu, Y [1 ]
Chen, XY
Li, Q
机构：
[1] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China
[2] Xiaogan Univ, Dept Chem, Xiaogan 432100, Peoples R China
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2004年 / 34卷 / 1-2期
基金：
中国博士后科学基金;
关键词：
chitosan; quaternary ammonium salt; microcalorimetry; microorganism; antimicrobial activity;
D O I：
10.1016/j.ijbiomac.2004.03.009
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The water-soluble quaternary ammonium salt of chitosan was synthesized by reaction of chitosan with glycidyl trimethylammonium chloride. It was characterized by Fourier transform infrared and carbon-13 magnetic resonance spectra. Its microbiostatic effects against Staphylococcus aureus, Escherichia coli and Candid albicans were explored by microcalorimetry. The antimicrobial activity of the quaternized chitosan was stronger in alkaline condition than that in weak acidic condition. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码：121 / 126
页数：6
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