Intron size correlates positively with recombination rate in Caenorhabditis elegans

被引:34
作者
Prachumwat, A [1 ]
DeVincentis, L [1 ]
Palopoli, MF [1 ]
机构
[1] Bowdoin Coll, Dept Biol, Brunswick, ME 04011 USA
关键词
D O I
10.1534/genetics.166.3.1585
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A negative correlation between intron size and recombination rate has been reported for the Drosophila melanogaster and human genomes. Population-genetic models suggest that this pattern could be caused by an interaction between recombination rate and the efficacy of natural selection. To test this idea, we examined variation in intron size and recombination rate across the genome of the nematode Caenorhabditis elegans. Interestingly, we found that intron size correlated positively with recombination rate in this species.
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收藏
页码:1585 / 1590
页数:6
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