HOSPITALIZATION RATES OF COMPLICATED PNEUMOCOCCAL COMMUNITY-ACQUIRED PNEUMONIA IS INCREASING IN TUSCAN CHILDREN

被引：4

作者：

Bonsignori, F. ^{[1
]}

Chiappini, E. ^{[1
]}

Orlandini, E. ^{[1
]}

Parretti, A. ^{[1
]}

Sollai, S. ^{[1
]}

Resti, M. ^{[1
]}

Galli, L. ^{[1
]}

Azzari, C. ^{[1
]}

De Martino, M. ^{[1
]}

机构：

[1] Anna Meyer Childrens Univ Hosp, Dept Sci Woman & Childs Hlth, Florence, Italy

来源：

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2013年 / 26卷 / 04期

关键词：

community acquired pneumonia; pneumococcal pneumonia; complicated pneumonia; pneumonia hospitalization rate; empyema; children; 7-valent pneumococcal conjugate vaccine (PCV7); CONJUGATE VACCINE; STREPTOCOCCUS-PNEUMONIAE; CHILDHOOD IMMUNIZATION; EMPYEMA; DISEASE; TRENDS; EPIDEMIOLOGY; ADMISSIONS; SEROTYPES; LIGURIA;

D O I：

10.1177/039463201302600421

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To provide epidemiological data on community-acquired pneumonia (CAP) and complicated CAP, a retrospective study was conducted on a partially vaccinated paediatric population. Data from children hospitalized for CAP in Tuscan hospitals between January 1(st), 1999 and December 31(st), 2009 were analysed. A total of 5,450 children with CAP were hospitalized. Annual hospitalization rates for CAP did not change significantly over the study period (x(2) for trend= 0.652; p=0.419). The total annual hospitalization rate for pneumococcal CAP varied according to age (28.04 per 100,000 children aged <= 5 years, 10.06 per 100,000 children aged 6-12 years and 0.98 per 100,000 children aged >= 13years). Hospitalization rates for pneumococcal CAP increased from 12.84 (95% CI:7.35-18.34) in 2001 to 45.4 (95% CI:35.93-54.90) per 100,000 children aged <= 5 years in 2009 (p < 0.0001). In addition, a significant increase of hospitalization rates for complicated CAP (from 6.07 in 1999 to 13.66 in 2009 per 100,000 children; P < 0.0001) and pneumococcal complicated CAP (from 0.19 in 1999 to 3.41 in 2009 per 100,000 children) over the study period were highlighted. Our epidemiological data confirm the decision to introduce the PCV13 vaccine, to satisfy the need to prevent a wider group of pneumococcal serotypes.

引用

页码：995 / 1005

页数：11

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