Enantioselective synthesis of the pyrroloquinoline core of the martinellines

被引：85

作者：

Nieman, JA ^{[1
]}

Ennis, MD ^{[1
]}

机构：

[1] Pharmacia & Upjohn Inc, Struct Analyt & Med Chem, Kalamazoo, MI 49001 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 10期

关键词：

D O I：

10.1021/ol0057030

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first enantioselective synthesis of the martinelline core (-)-3 is reported. The synthesis of (-)-3 from N-allyl-N-(benzyloxycarbonyl)-2-iodoaniline (12) proceeded in seven steps and 23% overall yield. In addition, the preparation of a carbocyclic model system is described.

引用

页码：1395 / 1397

页数：3

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