EBV-associated gastric carcinoma in high- and low-incidence areas for nasopharyngeal carcinoma

被引：10

作者：

Boysen, T. ^{[1
]}

Mohammadi, M. ^{[2
]}

Melbye, M. ^{[1
]}

Hamilton-Dutoit, S. ^{[3
]}

Vainer, B. ^{[2
]}

Hansen, A. V. ^{[1
]}

Wohlfahrt, J. ^{[1
]}

Friborg, J. ^{[1
]}

机构：

[1] Statens Serum Inst, Dept Epidemiol Res, DK-2300 Copenhagen S, Denmark

[2] Copenhagen Univ Hosp, Rigshosp, Dept Pathol, DK-2100 Copenhagen O, Denmark

[3] Aarhus Univ Hosp, Inst Pathol, DK-8000 Aarhus C, Denmark

来源：

BRITISH JOURNAL OF CANCER | 2009年 / 101卷 / 03期

基金：

英国医学研究理事会;

关键词：

Epstein-Barr virus; gastric carcinoma; nasopharyngeal carcinoma; EPSTEIN-BARR-VIRUS; CANCER; COHORT;

D O I：

10.1038/sj.bjc.6605168

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

BACKGROUND: Approximately 10% of gastric carcinomas are associated with Epstein-Barr virus (EBV). The Inuit in Greenland have a high incidence of EBV-associated nasopharyngeal carcinoma. METHODS: We conducted a population-based case-control study comparing gastric carcinomas in Greenland and in Denmark. RESULTS: The prevalence rate of EBV-associated gastric carcinomas was 8.5% in both populations. CONCLUSION: The findings of this study argue against a general susceptibility to EBV-associated carcinomas among the Inuit. British Journal of Cancer (2009) 101, 530-533. doi:10.1038/sj.bjc.6605168 www.bjcancer.com Published online 14 July 2009 (C) 2009 Cancer Research UK

引用

页码：530 / 533

页数：4

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