Secondary metabolites produced by endophytic fungus Paecilomyces variotii Bainier with antimicrobial activity against Enterococcus faecalis

被引：1
作者：
Oliveira Silva, M. R. [1 ,2 ]
Sena, K. Xisto [2 ]
Gusmao, N. Buarque [2 ]
机构：
[1] Univ Fed Pernambuco, Dept Mycol, Av Prof Morais Rego,1235, BR-50670901 Recife, PE, Brazil
[2] Univ Fed Pernambuco, Dept Antibiot, Lab Antimicrobial Assays, BR-50670901 Recife, PE, Brazil
来源：
CURRENT RESEARCH TOPICS IN APPLIED MICROBIOLOGY AND MICROBIAL BIOTECHNOLOGY | 2009年
关键词：
Antimicrobial Activity; Paecilomyces variotii; Endophytic Fungi; Enterococcus faecalis; TAXUS-MAIREI; MANGROVE; SUSCEPTIBILITY; TAXOL; SP;
D O I：
10.1142/9789812837554_0108
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Enterococcus faecalis is a Gram-positive bacteria considered an important emergent nosocomial pathogen. mainly due to its resistance to most antibiotics and responsible For a variety of human infections. In order to discover new bioactive secondary metabolites from microbial sources, the objective of this work was to evaluate the antimicrobial activity of the crude extract obtained from Paecilomyces variotii for eight clinical isolates of E. faecalis by the disk diffusion method. The results showed that all clinical isolates were inhibited by fungal extract, with inhibition zones ranging from 25 to 35.25 mm. In addition, the results also revealed resistance, in the microorganisms test, to antibiotics such as ciprofloxacin, cotrimoxazole, erythromycin, gentamicin, oxacillin and tetracycline.
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页码：519 / +
页数：2
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