Mitochondria in Mammalian Sperm Physiology and Pathology: A Review

被引：111

作者：

Pena, F. J. ^{[1
]}

Rodriguez Martinez, H. ^{[2
]}

Tapia, J. A. ^{[1
]}

Orteag Ferrusola, C. ^{[1
]}

Gonzalez Fernandez, L. ^{[1
]}

Macias Garcia, B. ^{[1
]}

机构：

[1] Univ Extremadura, Vet Teaching Hosp, Lab Spermatol, Caceres, Spain

[2] Swedish Univ Agr Sci SLU, Fac Vet Med & Anim Sci, Div Reprod, Uppsala, Sweden

来源：

REPRODUCTION IN DOMESTIC ANIMALS | 2009年 / 44卷 / 02期

关键词：

PERMEABILITY TRANSITION PORE; HUMAN SPERMATOZOA; OXIDATIVE STRESS; ANTIOXIDANT SUPPLEMENTATION; CRYOPRESERVATION PROCESS; DIFFERENT FRACTIONS; BOAR SPERMATOZOA; CELL-DEATH; MEMBRANE; APOPTOSIS;

D O I：

10.1111/j.1439-0531.2008.01211.x

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

While, for a long time, the role of mitochondria in sperm physiology and pathology has been largely ignored, recent research points out the mitochondria as a major organelle with key roles in sperm function both under physiological and biotechnological conditions. This paper briefly reviews these novel findings regarding the role of mitochondria in sperm, paying special attention to the most practical, readily applicable, aspects of the topic such as their role as a major source of the sublethal damage that sperm experiments after cryopreservation.

引用

页码：345 / 349

页数：5

共 63 条

[1] Proteomic changes in mammalian spermatozoa during epididymal maturation [J].

Aitken, R. John ;

Nixon, Brett ;

Lin, Minjie ;

Koppers, Adam J. ;

Lee, Yun H. ;

Baker, Mark A. .

ASIAN JOURNAL OF ANDROLOGY, 2007, 9 (04) :554-564

[2] Oxidative stress, sperm survival and fertility control [J].

Aitken, RJ ;

Baker, MA .

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2006, 250 (1-2) :66-69

[3] Redox activity associated with the maturation and capacitation of mammalian spermatozoa [J].

Aitken, RJ ;

Ryan, AL ;

Baker, MA ;

McLaughlin, EA .

FREE RADICAL BIOLOGY AND MEDICINE, 2004, 36 (08) :994-1010

[4] Changes in tyrosine phosphorylation associated with true capacitation and capacitation-like state in boar spermatozoa [J].

Bravo, MM ;

Aparicio, IM ;

Garcia-Herreros, M ;

Gil, MC ;

Peña, FJ ;

Garcia-Marin, LJ .

MOLECULAR REPRODUCTION AND DEVELOPMENT, 2005, 71 (01) :88-96

[5] Mitochondrial free radical generation, oxidative stress, and aging [J].

Cadenas, E ;

Davies, KJA .

FREE RADICAL BIOLOGY AND MEDICINE, 2000, 29 (3-4) :222-230

[6] Adenylate kinases 1 and 2 are part of the accessory structures in the mouse sperm flagellum [J].

Cao, Wenlei ;

Haig-Ladewig, Lisa ;

Gerton, George L. ;

Moss, Stuart B. .

BIOLOGY OF REPRODUCTION, 2006, 75 (04) :492-500

[7] Male infertility and mitochondrial DNA [J].

Carra, E ;

Sangiorgi, D ;

Gattuccio, F ;

Rinaldi, AM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 322 (01) :333-339

[8] Mitochondria: Dynamic organelles in disease, aging, and development [J].

Chan, David C. .

CELL, 2006, 125 (07) :1241-1252

[9] Estrogen and mitochondria: A new paradigm for vascular protection? [J].

Duckles, SP ;

Krause, DN ;

Stirone, C ;

Procaccio, V .

MOLECULAR INTERVENTIONS, 2006, 6 (01) :26-35

[10] Regulation of human male germ cell death by modulators of ATP production [J].

Erkkila, Krista ;

Kyttanen, Sauli ;

Wikstrom, Marten ;

Taari, Kimmo ;

Hikim, Amiya P. Sinha ;

Swerdloff, Ronald S. ;

Dunkel, Leo .

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2006, 290 (06) :E1145-E1154

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