In vitro screening of traditionally used medicinal plants in China against enteroviruses

被引：38
|
作者：
Guo, Jin-Peng [1 ]
Pang, Ji [1 ]
Wang, Xin-Wei [1 ]
Shen, Zhi-Qiang [1 ]
Jin, Min [1 ]
Li, Jun-Wen [1 ]
机构：
[1] Inst Environm & Hlth, Dept Environm & Hlth, Tianjin 300050, Peoples R China
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2006年 / 12卷 / 25期
关键词：
traditional used medicinal plant; China; antiviral activity; enterovirus; Sargentodoxa cuneata; (Oliv) Reld. et. Wils; Sophora tonkinensis Gapnep; Paeonia veitchii Lynch; Cyrtomium fortunei J. sm; Spatholobus suberectus Dunn;
D O I：
10.3748/wjg.v12.i25.4078
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
AIM: To search for new antiviral agents from traditional Chinese medicine, specifically anti-enterovirosuses agents. METHODS: The aqueous extracts (AE) of more than 100 traditionally used medicinal plants in China were evaluated for their in vitro anti-Coxsackie virus 133 activities with a MTT-based colorimetric assay. RESULTS: The test for AE of 16 plants exhibited anti-Coxsackie virus B3 activities at different magnitudes of potency. They can inhibit three steps (inactivation, adsorption and replication) during the infection. Among the 16 plants, Sargentodoxa cuneata (Oliv.) Rehd. et Wils., Sophora tonkinensis Gapnep., Paeonia veitchii Lynch, Spatholobus suberectus Dunn. and Cyrtomium fortunei J. sm. also have activity against other enterovirus, including Coxsackie virus 135, Polio virus I, Echo virus 9 and Echo virus 29. Cell cytotoxic assay demonstrated that all tested AE had CC50 values higher than their EC50 values. CONCLUSION: The sixteen traditionally used medicinal plants in. China possessed antiviral activity, and some of them merit further investigations. (C) 2006 The WJG Press. All rights reserved.
引用
收藏
页码：4078 / 4081
页数：4
相关论文
共 50 条
  • [1] In vitro screening of traditionally used medicinal plants in China against Enteroviruses
    Jin-Peng Guo
    World Journal of Gastroenterology, 2006, (25) : 4078 - 4081
  • [2] Screening of medicinal plants traditionally used in Peruvian Amazon for in vitro antioxidant and anticancer potential
    Tauchen, Jan
    Huml, Lukas
    Bortl, Ludvik
    Doskocil, Ivo
    Jarosova, Veronika
    Marsik, Petr
    Frankova, Adela
    Clavo Peralta, Zoyla Mirella
    Chuspe Zans, Maria-Elena
    Havlik, Jaroslav
    Lapcik, Oldrich
    Kokoska, Ladislav
    NATURAL PRODUCT RESEARCH, 2019, 33 (18) : 2718 - 2721
  • [3] Screening of traditionally used Tanzanian medicinal plants for antifungal activity
    Kisangau, Daniel P.
    Hosea, Ken M.
    Lyaruu, Herbert V. M.
    Joseph, Cosam C.
    Mbwambo, Zakaria H.
    Masimba, Pax J.
    Gwandu, Catherine B.
    Bruno, Lenta N.
    Devkota, Krishna P.
    Sewald, Norbert
    PHARMACEUTICAL BIOLOGY, 2009, 47 (08) : 708 - 716
  • [4] Traditionally Used Medicinal Plants of Armenia
    Ayvazyan, Arpine
    Zidorn, Christian
    PLANTS-BASEL, 2024, 13 (23):
  • [5] In vitro antibacterial activity of selected medicinal plants traditionally used in Vietnam against human pathogenic bacteria
    Thuy Thu Vu
    Kim, Hyungrok
    Vu Khac Tran
    Dang, Quang Le
    Hoa Thi Nguyen
    Kim, Hun
    Kim, In Seon
    Choi, Gyung Ja
    Kim, Jin-Cheol
    BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2016, 16
  • [6] In vitro anti-plasmodial activity of some traditionally used medicinal plants against Plasmodium falciparum
    Venkatesalu, V.
    Gopalan, N.
    Pillai, C. R.
    Singh, Vineeta
    Chandrasekaran, M.
    Senthilkumar, A.
    Chandramouli, N.
    PARASITOLOGY RESEARCH, 2012, 111 (01) : 497 - 501
  • [7] In vitro antibacterial activity of selected medicinal plants traditionally used in Vietnam against human pathogenic bacteria
    Thuy Thu Vu
    Hyungrok Kim
    Vu Khac Tran
    Quang Le Dang
    Hoa Thi Nguyen
    Hun Kim
    In Seon Kim
    Gyung Ja Choi
    Jin-Cheol Kim
    BMC Complementary and Alternative Medicine, 16
  • [8] In vitro anti-plasmodial activity of some traditionally used medicinal plants against Plasmodium falciparum
    V. Venkatesalu
    N. Gopalan
    C. R. Pillai
    Vineeta Singh
    M. Chandrasekaran
    A. Senthilkumar
    N. Chandramouli
    Parasitology Research, 2012, 111 : 497 - 501
  • [9] Anthelmintic screening of Zimbabwean plants traditionally used against schistosomiasis
    Molgaard, P
    Nielsen, SB
    Rasmussen, DE
    Drummond, RB
    Makaza, N
    Andreassen, J
    JOURNAL OF ETHNOPHARMACOLOGY, 2001, 74 (03) : 257 - 264
  • [10] MEDICINAL PLANTS TRADITIONALLY USED IN MALI FOR DYSMENORRHEA
    Sanogo, Rokia
    AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES, 2011, 8 (05) : 90 - 96
12345