A 62-MeV proton beam for the treatment of ocular melanoma at Laboratori Nazionali del Sud-INFN

被引:117
作者
Cirrone, GAP [1 ]
Cuttone, G
Lojacono, PA
Lo Nigro, S
Mongelli, V
Patti, IV
Privitera, G
Raffaele, L
Rifuggiato, D
Sabini, MG
Salamone, V
Spatola, C
Valastro, LM
机构
[1] Ist Nazl Fis Nucl, Lab Nazl Sud, I-95123 Catania, Italy
[2] Univ Catania, Dept Phys, I-95123 Catania, Italy
[3] Univ Catania, Inst Radiol, I-95123 Catania, Italy
关键词
ocular melanoma; proton beam; protontherapy;
D O I
10.1109/TNS.2004.829535
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
At the Istituto Nazionale di Fisica Nucleare-Laboratori Nazionali del Sud (INFN-LNS) in Catania, Italy, the first Italian protontherapy facility, named Centro di AdroTerapia e Applicazioni Nucleari Avanzate (CATANA) has been built in collaboration with the University of Catania. It is based on the use of the 62-MeV proton beam delivered by the K = 800 Superconducting Cyclotron installed and working at INFN-LNS since 1995. The facility is mainly devoted to the treatment of ocular diseases like uveal melanoma. A beam treatment line in air has been assembled together with a dedicated positioning patient system. The facility has been in operation since the beginning of 2002 and 66 patients have been successfully treated up to now. The main features of CATANA together with the clinical and dosimetric features will be extensively described; particularly, the proton beam line, that has been entirely built at LNS, with all its elements, the experimental transversal and depth dose distributions of the 62-MeV proton beam obtained for a final collimator of 25-mm diameter and the experimental depth dose distributions of a modulated proton beam obtained for the same final collimator. Finally, the clinical results over 1 yr of treatments, describing the features of the treated diseases will be reported.
引用
收藏
页码:860 / 865
页数:6
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