Voltammetric Analysis of Naproxen in Graphite Electrodes and Its Determination in Pharmaceutical Samples

被引：20

作者：

Aguilar-Lira, G. Y. ^{[1
]}

Alvarez Romero, G. A. ^{[1
]}

Rojas-Hernandez, A. ^{[2
]}

Paez-Hernandez, M. E. ^{[1
]}

Rodriguez-Avila, J. A. ^{[1
]}

Romero-Romo, M. A. ^{[3
]}

机构：

[1] Univ Autonoma Estado Hidalgo, Area Acad Quim, Mineral De La Reforma 42184, Hidalgo, Mexico

[2] Univ Autonoma Metropolitana Unidad Iztapalapa, Area Quim Anal, Mexico City 09340, DF, Mexico

[3] Univ Autonoma Metropolitana Azcapotzalco, Area Ingn Mat, Mexico City 02200, DF, Mexico

来源：

ELECTROANALYSIS | 2014年 / 26卷 / 07期

关键词：

Differential pulse voltammetry; Naproxen; Pharmaceutical samples; Graphite electrode; FORMULATIONS;

D O I：

10.1002/elan.201400119

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The present work discuses new findings in the electrochemistry of naproxen over graphite electrodes. This new approach, allows the proposal of a simple and competitive low-cost method to carry out naproxen's voltammetric quantification. Naproxen's indirect quantification through an adsorption anodic wave was performed at a graphite bar electrode using differential pulse voltammetry. An anodic current maximum was recorded at a potential of -0.3 V referred to a saturated Ag/AgCl reference electrode. The calibration plot having a correlation coefficient of 0.990, sensibility of 4.19 +/- 0.62 mu A cm(3) mu g(-1), with detection and quantification limits of 0.68 and 3.3 mu g cm(-3), respectively.

引用

页码：1573 / 1581

页数：9

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