The skin microbiome: potential for novel diagnostic and therapeutic approaches to cutaneous disease

被引：149

作者：

Grice, Elizabeth A. ^{[1
]}

机构：

[1] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA

来源：

SEMINARS IN CUTANEOUS MEDICINE AND SURGERY | 2014年 / 33卷 / 02期

基金：

美国国家卫生研究院;

关键词：

DEMODEX MITES; ATOPIC-DERMATITIS; BODY HABITATS; ABCC11; ALLELE; DIVERSITY; COMPLEMENT; CHILDREN; INFLAMMATION; ASSOCIATION; INFANTS;

D O I：

10.12788/j.sder.0087

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A vast diversity of microorganisms, including bacteria, fungi, viruses, and arthropods, colonize the human skin. Culture-independent genomic approaches for identifying and characterizing microbial communities have provided glimpses into the topographical, temporal, and interpersonal complexity that defines the skin microbiome. Identification of changes associated with cutaneous disease, including acne, atopic dermatitis, rosacea, and psoriasis, are being established. In this review, our current knowledge of the skin microbiome in health and disease is discussed, with particular attention to potential opportunities to leverage the skin microbiome as a diagnostic, prognostic, and/or therapeutic tool. (C) 2014 Frontline Medical Communications

引用

页码：98 / 103

页数：6

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