Necrotizing fasciitis

被引：4

作者：

Jansen-Winkeln, Boris ^{[1
]}

Langer, Stefan ^{[2
]}

Minh Hoang Do ^{[3
]}

Gockel, Ines ^{[1
]}

机构：

[1] Univ Klinikum Leipzig, AoR, Klin Viszeral Transplantat Thorax & Gefasschirurg, Liebigstr 20, D-04103 Leipzig, Germany

[2] Univ Klinikum Leipzig, AoR, Klin Orthopadie Unfall & Plast Chirurg, Leipzig, Germany

[3] Univ Klinikum Leipzig, AoR, Klin & Poliklin Urol, Leipzig, Germany

来源：

COLOPROCTOLOGY | 2019年 / 41卷 / 03期

关键词：

Fournier gangrene; Streptococcus groupA; Piperacillin; tazobactam drug combination; Clindamycin; Debridement; LABORATORY RISK INDICATOR; CLINICAL PRESENTATION; MICROBIOLOGY; DETERMINANTS; DIAGNOSIS; THERAPY; SCORE;

D O I：

10.1007/s00053-019-0370-0

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Necrotizing fasciitis is arare but always life-threatening disease, which necessitates a rapid diagnosis and immediate treatment. It can occur on the extremities as well as on the trunk and the perineum. It spreads rapidly along the fascia leading to septic shock. The mortality rate under intensive care treatment is approximately 20%. The pathogen spectrum ranges from mixed bacterial infections to groupA streptococci, clostridia and fungi. Clinically, the discrepancy between skin affection and systemic disease symptoms is remarkable. The diagnosis is primarily clinical and the key to successful treatment is rapid and radical surgical debridement combined with broad-spectrum antibiotic therapy under intensive patient monitoring.

引用

页码：223 / 232

页数：10

共 31 条

[1] [Anonymous], 1883, SEMIN MED
[2] What Is the Accuracy of Physical Examination, Imaging, and the LRINEC Score for the Diagnosis of Necrotizing Soft Tissue Infection?
April, Michael D.
Long, Brit
[J]. ANNALS OF EMERGENCY MEDICINE, 2019, 73 (01) : 22 - 24
[3] Laboratory risk indicator for necrotising fasciitis (LRINEC) score for the assessment of early necrotising fasciitis: a systematic review of the literature
Bechar, J.
Sepehripour, S.
Hardwicke, J.
Filobbos, G.
[J]. ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 2017, 99 (05) : 341 - 346
[4] Fernando SM, 2019, ANN SURG, V269, P58, DOI [10.1097/SLA.0000000000002774, 10.1097/sla.0000000000002774]
[5] NECROTIZING FASCIITIS - IMPORTANCE OF ROENTGENOGRAPHIC STUDIES FOR SOFT-TISSUE GAS
FISHER, JR
CONWAY, MJ
TAKESHITA, RT
SANDOVAL, MR
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1979, 241 (08): : 803 - 806
[6] BACTERIOLOGY OF NECROTIZING FASCIITIS
GIULIANO, A
LEWIS, F
HADLEY, K
BLAISDELL, FW
[J]. AMERICAN JOURNAL OF SURGERY, 1977, 134 (01) : 52 - 57
[7] Early diagnosis of necrotizing fasciitis
Goh, T.
Goh, L. G.
Ang, C. H.
Wong, C. H.
[J]. BRITISH JOURNAL OF SURGERY, 2014, 101 (01) : E119 - E125
[8] Herr M, 2011, UNFALLCHIRURG, V114, P197, DOI 10.1007/s00113-010-1893-6
[9] Triple diagnostics for early detection of ambivalent necrotizing fasciitis
Hietbrink, Falco
Bode, Lonneke G.
Riddez, Louis
Leenen, Luke P. H.
van Dijk, Marijke R.
[J]. WORLD JOURNAL OF EMERGENCY SURGERY, 2016, 11
[10] Necrotizing soft tissue infections. Clinical diagnosis and therapy decisions
Hungerer, S.
Ziegler, P.
Buehren, V.
Friederichs, J.
[J]. TRAUMA UND BERUFSKRANKHEIT, 2018, 20 : 67 - 72

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