Phantom limbs and neural plasticity

被引:127
作者
Ramachandran, VS [1 ]
Rogers-Ramachandran, D [1 ]
机构
[1] Univ Calif San Diego, Ctr Brain & Cognit, La Jolla, CA 92093 USA
关键词
D O I
10.1001/archneur.57.3.317
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The study of phantom limbs has received tremendous impetus from recent studies linking changes in cortical topography with perceptual experience. Systematic psychophysical testing and functional imaging studies on patients with phantom limbs provide 2 unique opportunities. First, they allow us to demonstrate neural plasticity in the adult human brain. Second, by tracking perceptual changes (such as referred sensations) and changes in cortical topography in individual patients, we can begin to explore how the activity of sensory maps gives rise to conscious experience. Finally, phantom limbs also allow us to explore intersensory effects and the manner in which the brain constructs and updates a 'body image' throughout life.
引用
收藏
页码:317 / 320
页数:4
相关论文
共 21 条
[1]   PHANTOM LOWER-LIMB AS A PERCEPTUAL MARKER OF NEURAL PLASTICITY IN THE MATURE HUMAN BRAIN [J].
AGLIOTI, S ;
BONAZZI, A ;
CORTESE, F .
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1994, 255 (1344) :273-278
[2]   Acute plasticity in the human somatosensory cortex following amputation [J].
Borsook, D ;
Becerra, L ;
Fishman, S ;
Edwards, A ;
Jennings, CL ;
Stojanovic, M ;
Papinicolas, L ;
Ramachandran, VS ;
Gonzalez, RG ;
Breiter, H .
NEUROREPORT, 1998, 9 (06) :1013-1017
[3]   Phantom face: Conscious correlate of neural reorganization after removal of primary sensory neurones [J].
Clarke, S ;
Regli, L ;
Janzer, RC ;
Assal, G ;
deTribolet, N .
NEUROREPORT, 1996, 7 (18) :2853-2857
[4]  
CRONHOLM B, 1951, Acta Psychiatr Neurol Scand Suppl, V72, P1
[5]   PHANTOM-LIMB PAIN AS A PERCEPTUAL CORRELATE OF CORTICAL REORGANIZATION FOLLOWING ARM AMPUTATION [J].
FLOR, H ;
ELBERT, T ;
KNECHT, S ;
WIENBRUCH, C ;
PANTEV, C ;
BIRBAUMER, N ;
LARBIG, W ;
TAUB, E .
NATURE, 1995, 375 (6531) :482-484
[6]   Bimanual coupling in amputees with phantom limbs [J].
Franz, EA ;
Ramachandran, VS .
NATURE NEUROSCIENCE, 1998, 1 (06) :443-444
[7]  
HALLIGAN PW, 1994, NEUROREPORT, V5, P1341, DOI 10.1097/00001756-199406270-00011
[8]   PHANTOM LIMBS AND THE CONCEPT OF A NEUROMATRIX [J].
MELZACK, R .
TRENDS IN NEUROSCIENCES, 1990, 13 (03) :88-92
[9]   SOMATOSENSORY CORTICAL MAP CHANGES FOLLOWING DIGIT AMPUTATION IN ADULT MONKEYS [J].
MERZENICH, MM ;
NELSON, RJ ;
STRYKER, MP ;
CYNADER, MS ;
SCHOPPMANN, A ;
ZOOK, JM .
JOURNAL OF COMPARATIVE NEUROLOGY, 1984, 224 (04) :591-605
[10]  
METZACK R, 1992, SCI AM, V266, P120