Solution-phase hexasaccharide synthesis using glucosyl iodides

被引：57

作者：

Lam, SN ^{[1
]}

Gervay-Hague, J ^{[1
]}

机构：

[1] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 12期

关键词：

D O I：

10.1021/ol025887d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHIC] Oligosaccharides composed of 1,6-glucosyl residues have been prepared from glucosyl iodides. The reactions are highly stereoselective, giving the a-glycosides as the only isolated products in yields ranging from 84% to 94%. Oligomer synthesis can take place in an iterative 1 + 1 + 1 fashion or in a convergent manner where dimer iodides serve as donors for higher order acceptors.

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页码：2039 / 2042

页数：4

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