Regorafenib inhibits ERK signaling and suppresses the growth of sorafenib-resistant cells in human hepatocellular carcinoma

被引：0
|
作者：
Hashiba, Tomomi [1 ]
Yamashita, Taro [1 ]
Okada, Hikari [1 ]
Nio, Kouki [1 ]
Hayashi, Takehiro [1 ]
Nomura, Yoshimoto [1 ]
Yoshida, Mariko [1 ]
Hayashi, Tomoyuki [1 ]
Oishi, Naoki [1 ]
Honda, Masao [1 ]
Kaneko, Shuichi [1 ]
机构：
[1] Kanazawa Univ, Grad Sch Med, Gastroenterol, Kanazawa, Ishikawa, Japan
来源：
HEPATOLOGY | 2015年 / 62卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
1953
引用
收藏
页码：1160A / 1160A
页数：1
相关论文
共 50 条
  • [21] Nrf2 signaling promotes cancer stemness, migration, and expression of ABC transporter genes in sorafenib-resistant hepatocellular carcinoma cells
    Gao, Luping
    Morine, Yuji
    Yamada, Shinichiro
    Saito, Yu
    Ikemoto, Tetsuya
    Tokuda, Kazunori
    Takasu, Chie
    Miyazaki, Katsuki
    Shimada, Mitsuo
    PLOS ONE, 2021, 16 (09):
  • [22] Impact of glucose metabolism on PD-L1 expression in sorafenib-resistant hepatocellular carcinoma cells
    Cho, Sua
    Kim, Wonjin
    Yoo, Dayoung
    Han, Yeonju
    Hwang, Hyemin
    Kim, Seunghwan
    Kim, Jimin
    Park, Sanghee
    Park, Yusun
    Jo, Hanhee
    Pyun, Jae-chul
    Lee, Misu
    SCIENTIFIC REPORTS, 2024, 14 (01)
  • [23] Impact of glucose metabolism on PD-L1 expression in sorafenib-resistant hepatocellular carcinoma cells
    Sua Cho
    Wonjin Kim
    Dayoung Yoo
    Yeonju Han
    Hyemin Hwang
    Seunghwan Kim
    Jimin Kim
    Sanghee Park
    Yusun Park
    HanHee Jo
    Jae-chul Pyun
    Misu Lee
    Scientific Reports, 14
  • [24] AG-1024 Sensitizes Sorafenib-Resistant Hepatocellular Carcinoma Cells to Sorafenib via Enhancing G1/S Arrest
    Zhou, Wei
    Lou, Weiyang
    Chen, Junru
    Ding, Bisha
    Chen, Binjie
    Xie, Haiyang
    Zhou, Lin
    Zheng, Shusen
    Jiang, Donghai
    ONCOTARGETS AND THERAPY, 2021, 14 : 1049 - 1059
  • [25] Targeting KDM1A attenuates Wnt/β-catenin signaling pathway to eliminate sorafenib-resistant stem-like cells in hepatocellular carcinoma
    Huang, Mengxi
    Chen, Cheng
    Geng, Jian
    Han, Dong
    Wang, Tao
    Xie, Tao
    Wang, Liya
    Wang, Ye
    Wang, Chunhua
    Lei, Zengjie
    Chu, Xiaoyuan
    CANCER LETTERS, 2017, 398 : 12 - 21
  • [26] Identification of key pathways and biomarkers in sorafenib-resistant hepatocellular carcinoma using bioinformatics analysis
    Huang, Danping
    Yuan, Weiqu
    Li, Hanmin
    Li, Shaodong
    Chen, Zuanguang
    Yang, Hongzhi
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 16 (03) : 1850 - 1858
  • [27] A novel strategy for sorafenib-resistant hepatocellular carcinoma: autotaxin Inhibition by PF-8380
    Kwak, Bong Jun
    Park, Jung Hyun
    Kim, Ok-Hee
    Lee, Dosang
    Hong, Tae Ho
    Lee, Sang Chul
    Kim, Kee-Hwan
    Choi, Ho Joong
    Kim, Say-June
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2025, 151 (03)
  • [28] Application of self-assembly peptides targeting the mitochondria as a novel treatment for sorafenib-resistant hepatocellular carcinoma cells
    Tae Ho Hong
    M. T. Jeena
    Ok-Hee Kim
    Kee-Hwan Kim
    Ho Joong Choi
    Kyung Hee Lee
    Ha-Eun Hong
    Ja-Hyoung Ryu
    Say-June Kim
    Scientific Reports, 11
  • [29] Application of self-assembly peptides targeting the mitochondria as a novel treatment for sorafenib-resistant hepatocellular carcinoma cells
    Hong, Tae Ho
    Jeena, M. T.
    Kim, Ok-Hee
    Kim, Kee-Hwan
    Choi, Ho Joong
    Lee, Kyung Hee
    Hong, Ha-Eun
    Ryu, Ja-Hyoung
    Kim, Say-June
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [30] Carbohydrate restriction inhibits malignant progression and survival of sorafenib-resistant murine hepatocellular carcinoma via reduction of PI3K/Akt/mTOR signaling
    Rudolph, I.
    Kettelhake, A.
    Zasada, C.
    Erdem, M.
    Kempa, S.
    Falk, C.
    Cramer, T.
    ONCOLOGY RESEARCH AND TREATMENT, 2016, 39 : 17 - 17
12345