Actin dynamics: Tropomyosin provides stability

被引：115
作者：
Cooper, JA [1 ]
机构：
[1] Washington Univ, Dept Cell Biol, Sch Med, St Louis, MO 63110 USA
来源：
CURRENT BIOLOGY | 2002年 / 12卷 / 15期
关键词：
D O I：
10.1016/S0960-9822(02)01028-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Tropomyosin stabilizes actin filaments, while ADF/cofilin promotes their disassembly. These two proteins compete with each other for binding to the actin filament, providing a critical balance for actin assembly in vivo.
引用
收藏
页码：R523 / R525
页数：3
相关论文
共 20 条
  • [1] Effects of chemical modification, tropomyosin, and myosin subfragment 1 on the yield strength and critical concentration of F-actin
    Adami, R
    Cintio, O
    Trombetta, G
    Choquet, D
    Grazi, E
    [J]. BIOCHEMISTRY, 2002, 41 (18) : 5907 - 5912
  • [2] Identification of a novel tropomodulin isoform, skeletal tropomodulin, that caps actin filament pointed ends in fast skeletal muscle
    Almenar-Queralt, A
    Lee, A
    Conley, CA
    de Pouplana, LR
    Fowler, VM
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (40) : 28466 - 28475
  • [3] Regulation of coiled-coil assembly in tropomyosins
    Araya, E
    Berthier, C
    Kim, E
    Yeung, T
    Wang, XR
    Helfman, DM
    [J]. JOURNAL OF STRUCTURAL BIOLOGY, 2002, 137 (1-2) : 176 - 183
  • [4] TROPOMYOSIN BINDING TO F-ACTIN PROTECTS THE F-ACTIN FROM DISASSEMBLY BY BRAIN ACTIN-DEPOLYMERIZING FACTOR (ADF)
    BERNSTEIN, BW
    BAMBURG, JR
    [J]. CELL MOTILITY AND THE CYTOSKELETON, 1982, 2 (01): : 1 - 8
  • [5] Inhibition of the Arp2/3 complex-nucleated actin polymerization and branch formation by tropomyosin
    Blanchoin, L
    Pollard, TD
    Hitchcock-DeGregori, SE
    [J]. CURRENT BIOLOGY, 2001, 11 (16) : 1300 - 1304
  • [6] TROPOMYOSIN STABILIZES THE POINTED END OF ACTIN-FILAMENTS BY SLOWING DEPOLYMERIZATION
    BROSCHAT, KO
    WEBER, A
    BURGESS, DR
    [J]. BIOCHEMISTRY, 1989, 28 (21) : 8501 - 8506
  • [7] Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion
    Chan, AY
    Bailly, M
    Zebda, N
    Segall, JE
    Condeelis, JS
    [J]. JOURNAL OF CELL BIOLOGY, 2000, 148 (03) : 531 - 542
  • [8] DESMARAIS V, 2002, IN PRESS J CELL SCI
  • [9] ISOLATION AND SOME STRUCTURAL AND FUNCTIONAL-PROPERTIES OF MACROPHAGE TROPOMYOSIN
    FATTOUM, A
    HARTWIG, JH
    STOSSEL, TP
    [J]. BIOCHEMISTRY, 1983, 22 (05) : 1187 - 1193
  • [10] DEPOLYMERIZATION OF F-ACTIN BY DEOXYRIBONUCLEASE-1
    HITCHCOCK, SE
    CARLSSON, L
    LINDBERG, U
    [J]. CELL, 1976, 7 (04) : 531 - 542
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