EFFECT OF CONSUMPTION OF PROBIOTICS AND SYNBIOTICS ON THE COMPOSITION OF INTESTINAL MICROFLORA

Effect of consumption of probiotics (bifidobacteria- and Lactobacillus acidophilus-containing yogurt) and synbiotics (probiotics with addition prebiotic [inulin]) was carried out using on the composition of microbiota in the human gut our in vivo study. Three groups: P (Probiotic), S (Synbiotic) and K (Control, without yogurt) by 22 healthy adults was used for this experiment. P and S groups had without consumption of probiotics for 10 days (adaptation phase). Then a daily serving of yogurt for 21 days. Control group without consumed of yogurt during of experiment. Fecal samples were collected at days: 0 (the end of adaptation phase), 7, 14, 21 (yogurt consumption) and 26, 28 (wash out period). The results of the study suggest that the human fecal bacterial community could be altered by consumption yogurt. After consumption of prebiotics/synbiotics increased counts of LAB, including Lactobacillus acidpophilus and bifidobakteria respectively. The bigest increase of bacterial counts between zero and 14th day of an experiment was observed in the species L. acidophilus. The same was true regarding the genus Bifidobacterium, where the addition of inulin indicated growth support. The group synbioitc is inhibited growth of E. coli during consumption. In this regard, our experiment confirmed the previous data that bifidobacteria can act antagonistic toward some genera of pathogenic bacteria.