Functional diversity of chitin synthases of Aspergillus nidulans in hyphal growth, conidiophore development and septum formation

被引：42
|
作者：
Horiuchi, Hiroyuki [1 ]
机构：
[1] Univ Tokyo, Dept Biotechnol, Bunkyo Ku, Tokyo 1138657, Japan
来源：
MEDICAL MYCOLOGY | 2009年 / 47卷
关键词：
chitin synthase; Aspergillus; cell wall; MOTOR-LIKE DOMAIN; CLASS-V; CLASS-I; DIFFERENTIAL EXPRESSION; WALL INTEGRITY; GENE; CHSC; CSMA; CONIDIATION; FUMIGATUS;
D O I：
10.1080/13693780802213332
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Fungal chitin synthases are classified into seven classes. Recent advances in genome sequence analyses have revealed that there are more than seven chitin synthase-encoding genes in the genome of filamentous ascomycete fungi. To clarify the functional differences among these genes in the morphogenesis and hyphal tip growth, we have cloned six chitin synthase-encoding genes from Aspergillus nidulans and analyzed their functions. The results obtained suggest that chitin synthases are structurally and functionally divergent and play crucial roles in the growth and morphogenesis of A. nidulans.
引用
收藏
页码：S47 / S52
页数：6
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