Highly Enantioselective Carbonyl-ene Reactions Catalyzed by In(III)-PyBox Complex

被引：60

作者：

Zhao, Jun-Feng ^{[1
]}

Tsui, Hoi-Yan ^{[1
]}

Wu, Pei-Jia ^{[1
]}

Lu, Jun ^{[1
]}

Loh, Teck-Peng ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Math & Phys Sci, Div Chem & Biol Chem, Singapore 637371, Singapore

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 49期

关键词：

D O I：

10.1021/ja807501a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly enantioselective carbonyl-ene reaction catalyzed by In(III)-pybox is described. Both 1, 1-disubstituted alkenes and 1,1,2-trisubstituted alkenes proceeded smoothly to give the ene products in high yields up to 97% and with excellent diastereoselectivity and enantioselectivities up to > 99:1 and 99%, respectively.

引用

页码：16492 / +

页数：3

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